| orphan drug | A pharmaceutical that has been abandoned or neglected during its development because it is seen as having only a limited potential for profit. Often a drug which only has a limited target population or which treats a rare disease, thus limiting its financial potential. (09 Oct 1997) |
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| orphan drug act | Law giving incentives to companies developing a drug for a rare disease. The act gives the developer of the first drug of any one type a 7-year exclusive right to market the new drug. (14 Nov 1997) |
| orphan drug production | Production of drugs or biologicals which are unlikely to be manufactured by private industry unless special incentives are provided by others. (12 Dec 1998) |
| targeted drug delivery | Delivering a drug to a specific site in the body where it has the greatest effect, instead of allowing it to diffuse to various sites, where it may cause damage or trigger side effects. (14 Nov 1997) |
| united states food and drug administration | An agency of the public health service concerned with the overall planning, promoting, and administering of programs pertaining to maintaining standards of quality of foods, drugs, therapeutic devices, etc. (12 Dec 1998) |
| fixed drug eruption | A type of drug eruption that recurs at a fixed site (or sites) following the administration of a particular drug; the lesions usually consist of intensely erythematous and purplish, sharply demarcated macules, and occasionally of herpetic vesicles; the affected areas undergo gradual involution, but flare and enlarge on readministration of the offending drug and may become hyperpigmented. Iodine eruption, an acneform or follicular eruption or granulomatous lesion caused by a reaction to systemic iodine or iodide administration. Kaposi's varicelliform eruption, a now rare complication of vaccinia superimposed on atopic dermatitis, with generalised vesicles and vesicopapules and high fever. Synonym: eczema vaccinatum. (05 Mar 2000) |
| food and drug administration | The U.S. Agency responsible for regulation of biotechnology foodproducts. The major laws under which the agency has regulatory powersinclude the Food, Drug, and Cosmetic act, and the Public Health Service Act. (09 Oct 1997) |
| food-drug interactions | The pharmacological result, either desirable or undesirable, of drugs interacting with components of the diet. (12 Dec 1998) |
| legislation, drug | Laws concerned with manufacturing, dispensing, and marketing of drugs. (12 Dec 1998) |
| ajowan oil | A volatile oil distilled from the fruit of Carum copticum, one of the sources of thymol; a carminative, aromatic, and expectorant. Synonym: ptychotis oil. (05 Mar 2000) |
| allspice oil | pimenta oil |
| almond oil | A fixed oil expressed from sweet almonds, the kernels of varieties of Prunus amygdalus; used in ointments. Bitter almond oil, a volatile oil from the dried ripe kernels of bitter almonds and from other kernels containing amygdalin; it contains between 2 and 4% of hydrocyanic acid and 95% of benzaldehyde. (05 Mar 2000) |
| apple oil | Isoamyl isovalerate;used as a sedative; formerly used in the treatment of gallstones because of its solvent action on cholesterol. Synonym: apple oil. (05 Mar 2000) |
| apricot kernel oil | See: persic oil. (05 Mar 2000) |
| arachis oil | Oil extracted from the kernels of one or more cultivated varieties of Arachis hypogaea (family Leguminosae); used as a solvent for intramuscular injections and in the preparation of foods. Synonym: arachis oil. (05 Mar 2000) |