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cystathionine beta-synthase <enzyme> A multifunctional pyridoxal phosphate enzyme. In the second stage of cysteine biosynthesis it catalyses the reaction of homocysteine with serine to form cystathionine with the elimination of water.
Chemical name: L-Serine hydro-lyase (adding homocysteine)
Registry number: EC 4.2.1.22
(12 Dec 1998)
cystathionine gamma-synthase o-succinylhomoserine (thiol)-lyase
cysteine synthase <enzyme> An enzyme that catalyses the biosynthesis of cysteine in microorganisms and plants from o-acetyl-l-serine and hydrogen sulfide.
Chemical name: O(3)-Acetyl-L-serine acetate-lyase (adding hydrogen sulfide)
Registry number: EC 4.2.99.8
(12 Dec 1998)
pristinamycin IIA synthase <enzyme> A heterodimer of snaa and snab proteins (snaa and snab gene products, respectively); catalyses the oxidation of piib to piia with fmnh2 and o2 as cofactors; from streptomyces pristinaespiralis.
Registry number: EC 1.3.99.-
Synonym: pii(a) synthase, piia synthase
(26 Jun 1999)
prostaglandin endoperoxide synthase <enzyme> An enzyme complex that catalyses the formation of prostaglandins from the appropriate unsaturated fatty acid, molecular oxygen, and a reduced acceptor.
See: cyclooxygenase
Chemical name: (5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase
Registry number: EC 1.14.99.1
(12 Dec 1998)
prostaglandin-E synthase <enzyme> Converts pgh to pge; part of prostaglandin synthase complex
Registry number: EC 5.3.99.3
Synonym: prostaglandin r2 e-isomerase, endoperoxide isomerase, prostaglandin endoperoxide e isomerase, prostaglandin h2 e-isomerase, pge2 isomerase, prostaglandin e2 isomerase, pgr2 e-isomerase, prostaglandin h2-prostaglandin e2 isomerase, prostaglandin e isomerase
(26 Jun 1999)
prostaglandin-F synthase <enzyme> Catalyses conversion of pgd2 to pgf2alpha; also converts pgh2 to pgf2alpha
Registry number: EC 1.1.1.188
Synonym: pgd2 11-keto reductase, pgf synthetase, pgf synthase, prostaglandin d2-NADPH-dependent ketoreductase, prostaglandin f synthetase, pgf2alpha synthase, prostaglandin d2 11-keto reductase
(26 Jun 1999)
pseudouridine 746-32 synthase <enzyme> A dual-specificity pseudouridine synthase; forms both pseudouridine 746 in e. Coli 23s ribosomal RNA and pseudouridine 32 in trna(phe); has 219 aa; mw 24 kD
Registry number: EC 5.4.99.-
Synonym: 23s RNA pseudouridine 746 synthase, psi746 synthase, trna(phe) pseudouridine 32 synthase, psi32 synthase
(26 Jun 1999)
psoralen synthase <enzyme> Nadph-dependent cytochrome p-450 monooxygenase which converts (+) marmesin by initial hydroxylation at c3', followed by release of water, acetone and psoralen
Registry number: EC 1.14.13.-
Synonym: psoralen 5-monooxygenase
(26 Jun 1999)
pteroylpolyglutamate synthase <enzyme> Catalyses formation of amide bond between the gamma-carboxyl group of a folate and the amino group of glutamic acid
Registry number: EC 6.3.1.-
(26 Jun 1999)
holo-ACP synthase <enzyme> An enzyme catalyzing transfer of the 4'-phosphopantetheinyl residue from CoA to a serine of apo-ACP (acyl carrier protein) to form holo-ACP, releasing adenosine 3',5'-bisphosphate; a required step if fatty acid biosynthesis is to function.
(05 Mar 2000)
homocitrate synthase <enzyme> Chemical name: 3-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acetylating)
Registry number: EC 4.1.3.21
Synonym: lys1 gene product, nifv gene product
(26 Jun 1999)
homocysteine cystathionine gamma-synthase <enzyme> Homocysteine and cystein yield cystathionine and h2s
Registry number: EC 4.4.-
Synonym: hccg-s
(26 Jun 1999)
putrescine synthase <chemical> Plant enzyme which has agmatine iminohydrolase (EC 3.5.3.12), putrescine transcarbamylase (EC 2.1.3.6), ornithine transcarbamylase (EC 2.1.3.3) and carbamate kinase (EC 2.7.2.2) activities
Chemical name: synthase, putrescine
(26 Jun 1999)
sepiapterin synthase <enzyme> Dihydroneopterin is converted to sepiapterin in the presence of one or more enzymes
Registry number: EC 1.1.-
(26 Jun 1999)
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