| end point | <chemistry> It is the completion point during a titration reaction where there are equal amounts of titrant and whatever is being titrated. It is usually evident by the first perceptible alteration of the colour of an added indicator. <immunology> It is the most dilute an antibody or antiserum solution can be while still detectably reacting with the antigen. <statistics> A category of data used to compare the outcome in different arms of a clinical trial. Common endpoints are severe toxicity, disease progression or fall in such surrogate markers as CD4 count, but sometimes death is used as an endpoint. (08 Mar 2000) |
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| end-point measurement | Analytical measurement at the end of a chemical reaction, as opposed to making the measurement while the reaction proceeds. (05 Mar 2000) |
| end-point nystagmus | A jerky, physiologic nystagmus occurring in a normal individual when attempts are made to fixate a point at the limits of the field of fixation. Synonym: deviational nystagmus. (05 Mar 2000) |
| end product | <biochemistry> The final product of after a series of reactions with enzymes in a biochemical metabolic pathway has taken place. (09 Oct 1997) |
| end product inhibition | <biochemistry, physiology> The process of the end product of a particular metabolic reaction inhibiting an allosteric enzyme involved in that reaction as the reaction starts again, thus breaking the reaction cycle. (09 Oct 1997) |
| end product repression | Catabolite repression in which the catabolite is an end product of a particular pathway. (05 Mar 2000) |
| end stage | The late, fully developed phase of a disease; e.g., in end-stage renal disease, a shrunken and scarred kidney that may result from a variety of chronic diseases that have become indistinguishable in their effect on the kidney. (05 Mar 2000) |
| end-stage renal disease | <nephrology> A patient with inadequate renal function to support life. Individuals with end-stage disease must rely in kidney dialysis or peritoneal dialysis to survive. End-stage renal disease may be caused by a number of problems including diabetes, sickle cell disease, hypertension and congenital renal disease (polycystic kidney disease). (27 Sep 1997) |
| end-systolic volume | The amount of blood in the ventricle at the end of the cardiac ejection period and immediately preceding the beginning of ventricular relaxation; a measurement of the adequacy of cardiac emptying, related to systolic function. (05 Mar 2000) |
| end-tidal | at the end of a normal expiration. (05 Mar 2000) |
| end-tidal sample | A sample of the last gas expired in a normal expiration, ideally consisting only of alveolar gas. (05 Mar 2000) |
| zero end-expiratory pressure | Airway pressure which, at the end of expiration, equals atmospheric pressure. (05 Mar 2000) |
| Krause's end bulbs | Nerve terminals in skin, mouth, conjunctiva, and other parts, consisting of a laminated capsule of connective tissue enclosing the terminal, branched, convoluted ending of an afferent nerve fibre; generally believed to be sensitive to cold. Synonym: corpuscula bulboidea, bulboid corpuscles. (05 Mar 2000) |
| flush end | <molecular biology> The ends of a blunt-end DNA molecule, where both strands in the double-stranded DNA molecule are even with each other rather than one strand being longer than the other. (09 Oct 1997) |