| central canal | The ependyma-lined lumen (cavity) of the neural tube, the cerebral part of which remains patent to form the ventricles of the brain, while the spinal part in the adult often is reduced to a solid strand of modified ependyma. Synonym: canalis centralis medullae spinalis, central canal of spinal cord, tubus medullaris. Synonym: syringocele. (05 Mar 2000) |
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| central canal of spinal cord | The ependyma-lined lumen (cavity) of the neural tube, the cerebral part of which remains patent to form the ventricles of the brain, while the spinal part in the adult often is reduced to a solid strand of modified ependyma. Synonym: canalis centralis medullae spinalis, central canal of spinal cord, tubus medullaris. Synonym: syringocele. (05 Mar 2000) |
| central canal of the vitreous | A minute canal running through the vitreous from the discus nervi optici to the lens, containing in foetal life a prolongation of the central artery of the retina, the hyaloid artery. See: vitreous, hyaloid artery. Synonym: canalis hyaloideus, central canal of the vitreous, Cloquet's canal, Stilling's canal. (05 Mar 2000) |
| central canals of cochlea | Centrally placed channels that convey vessels and nerves to the apical turns of the cochlea. Synonym: canales longitudinales modioli, central canals of cochlea. (05 Mar 2000) |
| central cataract | Congenital cataract limited to the embryonic nucleus. (05 Mar 2000) |
| central cementifying fibroma | <tumour> A microscopic variant of a central ossifying fibroma. (05 Mar 2000) |
| central complex | In an enzyme-catalyzed reaction, the structural complex of the enzyme and all of the enzyme's substrates (or the enzyme with all of the enzyme's products) equivalent to the binary complex for a one-substrate enzyme. Compare: binary complex, Michaelis complex. (05 Mar 2000) |
| central cord syndrome | <syndrome> Quadriparesis most severely involving the distal upper extremities, with or without sensory loss and bladder dysfunction, usually due to ischemia from osteophytic or traumatic compression of the central part of the cervical spinal cord and/or artery. (05 Mar 2000) |
| central core disease | A congenital myopathy characterised by hypotonia, delay of motor development in infancy, and nonprogressive or slowly progressive muscle weakness; on biopsy the central core of muscle fibres stains abnormally, myofibrils are abnormally compact, and there is virtual absence of mitochondria and sarcoplasmic reticulum; histochemically, the cores are devoid of oxidative enzyme, phosphorylase, and ATPase activity; autosomal dominant inheritance, often subclinical. (05 Mar 2000) |
| central core disease of muscle | <neurology> One of the conditions that produces floppy baby syndrome. It causes hypotonia (floppiness) in the newborn baby, slowly progressive muscle weakness, and muscle cramps after exercise. Muscle biopsy shows a key diagnostic finding (absent mitochondria in the centre of many type I muscle fibres). The disease is inherited as a dominant trait. The CCD gene is on chromosome 19 (and involves ryanodine receptor-1). Inheritance: autosomal dominant. (12 Dec 1998) |
| central deafness | Deafness due to disorder of the auditory system of the brainstem or cerebral cortex. (05 Mar 2000) |
| central dogma | <molecular biology> The main principle of molecular biology, coined by Francis Crick, which states that genetic information flows from DNA to RNA to protein. (09 Oct 1997) |
| Central European tick-borne encephalitis virus | One of the virus's of the tick-borne encephalitis complex of group B arboviruses (genus Flavivirus); the causative agent of tick-borne encephalitis (Central European subtype). (05 Mar 2000) |
| Central European tick-borne fever | 1. (Central European subtype) tick-borne meningoencephalitis caused by a flavivirus closely related to the virus causing the Far Eastern type; it is transmitted by Ixodes ricinus, also by infected raw milk, especially that of goats. Synonym: biundulant meningoencephalitis, Central European tick-borne fever, diphasic milk fever, Russian spring-summer encephalitis (Western subtype). 2. (Eastern subtype) tick-borne encephalitis, a severe form of encephalitis caused by a flavivirus, a virus belonging to the Flaviviridae family, and transmitted by ticks (Ixodes pertulcatus and I. Ricinus). Synonym: Russian tick-borne encephalitis. (05 Mar 2000) |
| central excitatory state | The building up of excitatory influences produced by individual impulses finally causes firing of the next neuron. (05 Mar 2000) |