| insulin receptor substrate-1 protein | <chemical> Amino acid sequence given in first source; a 180 kD protein that contains multiple phosphorylated tyrosine residues after insulin stimulation; human and rat forms (hirs-1 and irs-1) are homologous Synonym: insulin receptor substrate-1-like protein, irs-1 protein, irs-1 gene product, hirs-1 protein, hirs-1 gene product, insulin receptor substrate 1, insulin receptor substrate-1 (05 Dec 1998) |
|---|---|
| insulin resistance | Many people with noninsulin-dependent diabetes produce enough insulin, but their bodies do not respond to the action of insulin. This may happen because the person is overweight and has too many fat cells, which do not respond well to insulin. Also, as people age, their body cells lose some of the ability to respond to insulin. Insulin resistance is also linked to high blood pressure and high levels of fat in the blood. Another kind of insulin resistance may happen in some people who take insulin injections. They may have to take very high doses of insulin every day (200 units or more) to bring their blood glucose (sugar) down to the normal range. (09 Oct 1997) |
| insulin shock | A severe condition that occurs when the level of blood glucose (sugar) drops quickly. The signs are shaking, sweating, dizziness, double vision, convulsions, and collapse. Insulin shock may occur when an insulin reaction is not treated quickly enough. See: hypoglycaemia. (09 Oct 1997) |
| insulin shock treatment | Formerly used treatment for serious mental disorders in which the patient was given insulin to induce a seizure; supplanted by electroshock therapy. (05 Mar 2000) |
| insulin-stimulating peptide | <chemical> 71-amino acid containing peptide; corresponds to residues 115-143 and 144-184 of bovine serum albumin with the exception of a tyrosine insertion between residues 155 and 156; consists of two chains with mw 5000 and 3400 for each chain Synonym: h-isp, insulin-stimulating protein (05 Dec 1998) |
| insulin unit | The activity contained in 1/22 mg of the international standard of zinc-insulin crystals. (05 Mar 2000) |
| ultralente insulin | A form of zinc precipitated insulin in suspension in which the particle size is large, and thus release into the bloodstream after subcutaneous injection is slow; it can be mixed with other insulins having different particle sizes to achieve different durations of activity. Can be derived from porcine, bovine, or genetically engineered human type. (05 Mar 2000) |
| lente insulin | A sterile buffered suspension with zinc chloride, containing 40 or 80 units per ml; the solid phase of the suspension consists of a mixture of 7 parts of crystalline insulin and 3 parts of amorphous insulin. Synonym: lente insulin. (05 Mar 2000) |
| adenoviruses, human | Species of the genus mastadenovirus, causing a wide range of diseases in humans. Infections are mostly asymptomatic, but can be associated with diseases of the respiratory, ocular, and gastrointestinal systems. (12 Dec 1998) |
| adenovirus infections, human | Respiratory and conjunctival infections caused by 33 identified serotypes of human adenoviruses. (12 Dec 1998) |
| antigens, human platelet | Human alloantigens expressed only on platelets, specifically on platelet membrane glycoproteins. These platelet-specific antigens are immunogenic and can result in pathological reactions to transfusion therapy. (12 Dec 1998) |
| bites, human | Bites inflicted by humans. (12 Dec 1998) |
| bonding, human-pet | The emotional attachment of individuals to pets. (12 Dec 1998) |
| packed human blood cells | Whole blood from which plasma has been removed; may be prepared any time during the dating period of the whole blood from which it is derived, but not later than six days after the blood has been drawn if separation of plasma and cell's is achieved by centrifugation. (05 Mar 2000) |
| papilloma virus, human | A family of over 60 viruses responsible forcausing warts. The majority of the viruses produce warts on the hands, fingers, and even the face. most of these viruses are innocuous, causing nothing more than cosmetic concerns. Several types of HPV are confined primarily to the moist skin of the genitals, producing genital warts and elevating the risk for cancer of the cervix. These viruses that cause wartlike growths on the genitals and contrribute to cancer of the cervix are sexually transmitted. (12 Dec 1998) |