| ISWI | incisional surgical wound infection |
|---|---|
| ISY | intrasynovial |
| ISM | intersegmental muscle |
|---|---|
| ISMN | 5-isosorbide mononitrate |
| ISNT | In situ nick translation |
| ISO | DL-isoproterenol |
| ISO | International Standard Organisation |
| ISO | Isoflurane |
| ISO | Isoprenaline |
| ISO | Isoprinosine |
| isoniazid | Isonicotinic acid hydrazide |
| ISOP | Isoproterenol |
| island disease | See Typhus, scrub. (12 Dec 1998) |
|---|---|
| island fever | See Typhus, scrub. (12 Dec 1998) |
| island flap | A flap in which the pedicle consists solely of the supplying artery and vein(s), sometimes including a nerve. (05 Mar 2000) |
| island of Reil | 1. An oval region of the cerebral cortex overlying the extreme capsule, lateral to the lenticular nucleus, buried in the depth of the fissura lateralis cerebri (sylvian fissure). Synonym: insular area, insular cortex, island of Reil. Synonym: island. 3. Any circumscribed body or patch on the skin. Origin: L. Island (05 Mar 2000) |
| islands of Calleja | Dense clusters of very small nerve cells (granule cells) characteristic of the olfactory tubercle at the base of the forebrain. (05 Mar 2000) |
| isle | 1. An island. 2. <entomology> A spot within another of a different colour, as upon the wings of some insects. Origin: OF. Isle, F. Ile, L. Insula; cf. Lith. Sala. Cf. Insulate. Source: Websters Dictionary (01 Mar 1998) |
| islet | A small island. (05 Mar 2000) |
| islet amyloid peptide | <hormone, protein> Peptide of 37 amino acids that selectively inhibits insulin stimulated glucose uptake in muscle. Structurally related to calcitonin gene-related peptide. (15 Oct 1997) |
| islet cell | <pathology> Cells of the Islets of Langerhans within the pancreas. See: A cells, B-cells, D cells. (18 Nov 1997) |
| islet cell adenoma | <tumour> A benign neoplasm of the pancreas composed of tissue similar in structure to that of the islets of Langerhans; it may contain functioning beta cells, and may cause hypoglycaemia. See: insulinoma. Synonym: nesidioblastoma. (05 Mar 2000) |
| islet cell antibodies | In first-degree relatives of probands with insulin-dependent diabetes mellitus the presence of high titre ICA of the IgG cytoplasmic variety (IgG -ICA) and ICA of the complement-fixing subgroup (CF-ICA) confer a relative risk of 75 for development of insulin-dependent diabetes mellitus. The presence of ICA combined with a decrease in the first-phase of insulin secretion ( less than 25 micro U/mL) is predictive with a 95% likelihood of the development of insulin-dependent diabetes mellitus within 12 months. Reproducible results among laboratories are possible with careful attention to selection of the human pancreas as substrate as well as to the use of dilutions to generate standard curves and to the conversion of results to units. The prozone phenomena described elsewhere are not common in our experience. Fifty percent of relatives with a single positive ICA test will develop insulin-dependent diabetes mellitus within 10 years, and 60-80% of relatives with both ICA and insulin autoantibodies (IAA) will develop insulin-dependent diabetes mellitus within 10 years. The predictive value for health of negative results for ICA and IAA is almost 99%. Strong, persistently positive ICA (i.e., 40 JDF U or greater), especially if accompanied by markedly decreased insulin secretion, are the best predictors of subsequent development of insulin-dependent diabetes mellitus. The 64 kD beta-cell autoantigen long thought to be an important target for ICA is not yet available from expression cloning despite efforts by several groups.13 ICA positivity correlates with rapid loss of C-peptide secretory capacity in newly diagnosed ICA-positive insulin-dependent diabetes mellitus. The predictive values of ICA for development of insulin-dependent diabetes mellitus within 10 years in first-degree relatives of patients with insulin-dependent diabetes mellitus increase from 40% at low levels of ICA to 100% at high levels, whereas the sensitivity is 88% at low levels and 31% at high levels. In general, the risk of insulin-dependent diabetes mellitus in relatives of probands increases with titre of ICA, is greater in multiplex families, and is increased in those less than 10 years of age with positive ICA. Although the prevalence of ICA in Japanese with autoimmune thyroid disease resembles that in Caucasians, the incidence of insulin-dependent diabetes mellitus in the Japanese population is only 1/30 - 1/50 that in Caucasians. Prediabetics positive for ICA and IAA have increased suppressor-inducer (CD45R) and decreased helper-inducer (CDw29) peripheral blood lymphocytes. In two randomised, prospective, placebo-controlled studies of recent-onset insulin-dependent diabetes mellitus, cyclosporine immunosuppression increased the rate of non-insulin-requiring remissions as well as beta-cell function during drug treatment. Although 12 months of cyclosporine therapy decreases titres of ICA and insulin antibodies (IA) and increases glucagon-stimulated levels of serum C-peptide, the determination of ICA and IA and HLA-DR type are of no predictive value in selecting recent- onset insulin-dependent diabetes mellitus. Patients for cyclosporine immunointervention. Genetic control of autoimmunity in insulin-dependent diabetes mellitus is reviewed. EIA for autoantibodies to a 64 kD islet-cell protein is promising for prediction of insulin-dependent diabetes mellitus, but sensitivity and specificity are still suboptimal. See also: insulin antibodies. (05 Mar 2000) |
| islet cell antigen-related protein-tyrosine phosphatase | <enzyme> Receptor-like autoantigen found in insulin-dependent diabetes; genbank l76258 Registry number: EC 3.1.3.- Synonym: iar ptp (26 Jun 1999) |
| islet neogenesis-associated protein | <chemical> Constituent of ilotropin; stimulates proliferation of pancreatic ductal cells in vitro; from hamsters and humans; amino acid sequence given in first source Synonym: ingap protein, ingap gene product (05 Dec 1998) |
| islet tissue | <anatomy> Groups of cells found within the pancreas: A cells and B-cells secrete insulin and glucagon. See: D cells. (18 Nov 1997) |
| islet-cell-stimulating antibodies | <immunology> Autoantibodies to a putative beta-cell receptor; stimulate the release of insulin both in rodents and man; may be analogous to the thyroid stimulating antibodies that cause grave's hyperthyroidism Synonym: icsta (05 Dec 1998) |
Synonyms : Bis(1-methylethyl) Phosphorofluoridate, Di-isopropylphosphorofluoridate, Diisopropylphosphofluoridate, Dyflos, Floropryl, Fluorostigmine, Merck Brand of Isoflurophate, Di isopropylphosphorofluoridate
Synonyms : Alloisoleucine, Isoleucine, L-Isomer, L-Isoleucine, Isoleucine, L Isomer, L-Isomer Isoleucine
Synonyms : Ile-tRNA Ligase, Isoleucyl-tRNA Synthetase, Ile tRNA Ligase, Isoleucine tRNA Ligase, Isoleucyl tRNA Synthetase, Ligase, Ile-tRNA, Ligase, Isoleucine-tRNA, Synthetase, Isoleucyl-tRNA
Synonyms :
Synonyms :
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| ischemia |
local anemia in a given body part sometimes resulting from vasoconstriction or thrombosis or embolism
Ãâó: wordnet.princeton.edu/perl/webwn
|
|---|---|
| ischia |
a volcanic island (part of Campania) in the Tyrrhenian Sea at the north end of the Bay of Naples
Ãâó: wordnet.princeton.edu/perl/webwn
|
| isocyanate |
a salt or ester of isocyanic acid
Ãâó: wordnet.princeton.edu/perl/webwn
|
| issue |
an important question that is in dispute and must be settled; "the issue could be settled by requiring public education for everyone"; "politicians never discuss the real issues" one of a series published periodically; "she found an old issue of the magazine in her dentist's waiting room" the act of providing an item for general use or for official purposes (usually in quantity); "a new issue of stamps"; "the last issue of penicillin was over a month ago" topic: some situation or event that is thought about; "he kept drifting off the topic"; "he had been thinking about the subject for several years"; "it is a matter for the police" supplies (as food or clothing or ammunition) issued by the government offspring: the immediate descendants of a person; "she was the mother of many offspring"; "he died without issue" consequence: a phenomenon that follows and is caused by some previous phenomenon; "the magnetic effect was greater when the rod was lengthwise"; "his decision had depressing consequences for business"; "he acted very wise after the event" publish: prepare and issue for public distribution or sale; "publish a magazine or newspaper" return: the income or profit arising from such transactions as the sale of land or other property; "the average return was about 5%" circulate or distribute or equip with; "issue a new uniform to the children"; "supply blankets for the beds" bring out an official document (such as a warrant) emergence: the becoming visible; "not a day's difference between the emergence of the andrenas and the opening of the willow catkins" exit: an opening that permits escape or release; "he blocked the way out"; "the canyon had only one issue" come out of; "Water issued from the hole in the wall"; "The words seemed to come out by themselves" write out: make out and issue; "write out a check"; "cut a ticket"; "Please make the check out to me" the act of issuing printed materials
Ãâó: wordnet.princeton.edu/perl/webwn
|
| isoflurane |
a widely used inhalation anesthetic
Ãâó: wordnet.princeton.edu/perl/webwn
|
| IS | Athenian rhetorician and orator (436-338 BC) |
|---|---|
| IS | a salt or ester of isocyanic acid |
| IS | an acid known only in the form of its esters |
| IS | containing a closed ring of atoms of the same kind especially carbon atoms |
| IS | quillworts |
| IS | aquatic or marsh-growing fern allies |
| IS | type and genus of the Isoetaceae and sole extant genus of the order Isoetales |
| IS | a widely used inhalation anesthetic |
| IS | either of a pair of conjugating gametes of the same size and structure |
| IS | (biology) reproduction by the union or fusion of games of the same size and structure |
| IS | an imaginary line connecting points on the Earth's surface where the magnetic declination is the same |
| IS | an imaginary line connecting points on the Earth's surface where the magnetic declination is the same |
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