| skin diseases, genetic | Diseases of the skin with a genetic component, usually the result of various inborn errors of metabolism. (12 Dec 1998) |
|---|---|
| suppression, genetic | The restoration of the wild-type phenotype in an organism possessing a mutationally altered genotype. The effects of the mutation may be suppressed by a second "suppressor" mutation on a different gene, by a suppressor mutation on the same gene but located at a distance from the site of the primary mutation, or by the presence of a cytoplasmic suppressor due to a change in non-chromosomal DNA. (12 Dec 1998) |
| transcription, genetic | The transfer of genetic information from DNA to messenger RNA by DNA-directed RNA polymerase. It includes reverse transcription and transcription of early and late genes expressed early in an organism's life cycle or during later development. (12 Dec 1998) |
| transduction, genetic | Transfer of bacterial DNA by phages from the infected bacterium in which the DNA originates to another bacterium. (12 Dec 1998) |
| transformation, genetic | The unidirectional transfer and incorporation of foreign DNA by prokaryotic or eukaryotic cells and the subsequent recombination of part or all of that DNA into the cell's genome. (glossary of genetics: classical and molecular, 5th ed) (12 Dec 1998) |
| translation, genetic | Formation of peptides on ribosomes, directed by messenger RNA. (12 Dec 1998) |
| epistasis, genetic | A form of gene interaction whereby one gene interferes with the phenotypic expression of another nonallelic gene or genes. Genes whose expression is altered by nonallelic genes are said to be "hypostatic" or to exhibit "hypostasis". (12 Dec 1998) |
| accumulation analysis | A technique in which an intermediate of a metabolic pathway accumulates due to selective inhibition of a particular step in that pathway or in a mutant that is deficient in a certain step. The intermediate is then isolated, analyzed, and identified. (05 Mar 2000) |
| activation analysis | <radiobiology> Method for identifying and measuring chemical elements in a sample of material. Sample is first made radioactive by bombardment with neutrons, charged particles, or gamma rays. Newly formed radioactive atoms in the sample then give off characteristic radiations (such as gamma rays) that tell what kinds of atoms are present, and how many. (09 Oct 1997) |
| actuarial analysis | The application of probability and statistical methods to calculate the risk of occurrence of any event, such as onset of illness, recurrent disease, hospitalization, disability, or death. It may include calculation of the anticipated money costs of such events and of the premiums necessary to provide for payment of such costs. (12 Dec 1998) |
| amino acid analysis | Determination and identification of amino acid content of a macromolecule, identification of a specific amino acid in macromolecules, often a mutated protein, identification and quantitation of amino acid content in blood plasma or urine; a key diagnostic aid. (05 Mar 2000) |
| analysis | <technique> The separation into component parts or elements, the act of determining the component parts of a substance. Origin: Gr. Lysis = dissolution (18 Nov 1997) |
| analysis of variance | A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable. (12 Dec 1998) |
| base sequence analysis | <molecular biology> A method, sometimes automated, for determining the base sequence. (09 Oct 1997) |
| bite analysis | A study of the relations of the occlusal surfaces of opposing teeth and their effect upon related structures. Synonym: bite analysis. (05 Mar 2000) |