| GM activator p. |
sphingolipid activator p.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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|---|---|
| GM-CSF |
granulocyte-macrophage colony-stimulating factor.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| GM1 g. |
an autosomal recessive disorder due to a deficiency of lysosomal β-galactosidase activity, with accumulation of ganglioside GM1, glycoproteins, and keratan sulfate; it occurs as several forms, decreasing in severity with increasing age of onset. The infantile, or type I, form is characterized by onset at birth, severe retardation of mental and motor development, cerebral degeneration, dysostosis multiplex, hepatosplenomegaly, early blindness, coarse facies, edema, seizures, hypotonia, hyperacusis, dysarthria, and sometimes cherry-red macular spot; death occurs by the age of 2. The juvenile, or type II, form is characterized by onset between 6 and 20 months, accumulation of ganglioside GM1 in brain but not viscera, seizures, late blindness, spasticity, and ataxia; death occurs between 3 and 10 years of age. The adult, or type III, form is characterized by onset in the teens, spasticity, and dysarthria, with little intellectual impairment and survival into the third decade.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| GM2 g. |
1. a lysosomal storage disease characterized by abnormal accumulation of ganglioside GM2 and related glycoconjugates due to a deficiency of activity of specific hexosaminidase isozymes; it occurs as three clinically similar but biochemically distinct variants named for the isozyme still present in the tissues of those affected. 2. GM2 g., variant B.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| GM2 g., type I |
the infantile form of GM2 g., variant B.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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