| polymerase, DNA | Enzyme that catalyses (speeds) the polymerization of DNA. DNA polymerase uses preexisting nucleic acid templates and assembles the DNA from deoxyribonucleotides. (12 Dec 1998) |
|---|---|
| polymerase, DNA or RNA | Enzymes that catalyse the synthesis of nucleic acids on pre-existing nucleic acid templates, assembling RNA from ribonucleotides or DNA from deoxyribonucleotides. (05 Mar 2000) |
| covalently closed circular DNA | <molecular biology> A circular molecule of double-stranded DNA which is supercoiled, or coiled up on itself due to internal tensions, because there are no breaks in the phosphate backbone (upon which the nucleotide bases are mounted) to relieve the tensions and allow it to form an open circle. (09 Oct 1997) |
| cytosine-DNA glycosidase | <enzyme> Acts on uv-irradiated DNA at modified cytosine residues which are not pyrimidine dimers Registry number: EC 3.2.2.- Synonym: cytosine-DNA glycosylase (26 Jun 1999) |
| hemimethylated DNA | <molecular biology> Duplex DNA where only one of the two strands are methylated and is important for regulating and protecting DNA. (13 Nov 1997) |
| satellite DNA | <molecular biology> DNA, usually containing highly repetitive sequences, that has a base composition (and thus density) sufficiently different from that of normal DNA that it sediments as a distinct band in caesium chloride density gradients. (18 Nov 1997) |
| herpes simplex virus DNA polymerase | <enzyme> 3'-5'-exonuclease activity is associated with herpes simplex virus DNA polymerase; interacts with hsv-1 ul42 protein Registry number: EC 3.1.11.- Synonym: hsv DNA polymerase, polymerase associated exonuclease, herpes simplex virus 1 ul30 polymerase, hsv-1 ul30 protein, DNA polymerase ul30, hsv-1 (26 Jun 1999) |
| Schizosaccharomyces pombe DNA endonuclease | <enzyme> Cleaves the phosphodiester bond immediately 5' of either cyclobutane pyrimidine dimers or 6-4 pyrimidine pyrimidones of uv-damaged DNA Registry number: EC 3.1.25.- Synonym: uv damage endonuclease, s. Pombe DNA endonuclease, uve1 gene product, spde (26 Jun 1999) |
| heteroduplex DNA | <molecular biology> This is DNA that contains complementary strands from two different DNA molecules with similar sequences. (09 Oct 1997) |
| highly repetitive DNA | <molecular biology> The fraction of the eukaryotic genome which consists of a short sequence of nucleotides that is repeated thousands of times all over the genome. Highly repetitive DNA is very similar to satellite DNA. (09 Oct 1997) |
| PspPI DNA methyltransferase | <enzyme> Methylates first cytosine in ggncc Registry number: EC 2.1.1.- Synonym: psppi methyltransferase, mtase (psppi), psppim gene product (26 Jun 1999) |
| selfish DNA | <molecular biology> DNA that seemingly exists only for the sake of existing and is never expressed in the phenotype. (09 Oct 1997) |
| sequence analysis, DNA | A multistage process that includes DNA cloning, physical mapping, subcloning, sequencing, and information analysis. New technological advances have led to the automation of certain steps in this process and contribute to the potential for large-scale DNA sequencing efforts. (12 Dec 1998) |
| Pyrococcus sp GB-D DNA polymerase | <enzyme> Thermophilic enzyme from the archaeon pyrococcus; used in pcr site-directed mutagenesis Registry number: EC 2.7.7.- Synonym: gb-d polymerase (26 Jun 1999) |
| hybrid DNA | <molecular biology> A double-stranded DNA molecule which was made by hybridising two single-stranded DNA molecules from two different sources. If the two single-stranded DNA molecules have enough nucleotide sequences in common, they are able to form hydrogen bonds to each other's common sequences. (09 Oct 1997) |