| dihydrolipoamide S- |
[EC 2.3.1.12] an enzyme of the transferase class that is a component of the multienzyme pyruvate dehydrogenase complex (q.v.). The enzyme catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA; the enzyme is itself the physiological lipoamide in the reaction. Called also dihydrolipoyltransacetylase.
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| dihydrolipoamide acyltransferase |
an enzyme of the transferase class that is the lipoamide component of the multienzyme branched-chain α-keto acid dehydrogenase complex (q.v.). The enzyme catalyzes the transfer of the decarboxylated branched-chain acyl moiety to coenzyme A via its own lipoic acid group.
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| dihydrolipoamide dehydrogenase |
[EC 1.8.1.4] an enzyme of the oxidoreductase class that catalyzes the regeneration of lipoamide from dihydrolipoamide, reducing NAD+. The enzyme contains FAD and is a component of several oxidative decarboxylation enzyme complexes: branched-chain α-keto acid dehydrogenase complex, α-ketoglutarate dehydrogenase complex, and pyruvate dehydrogenase complex; deficiency of the enzyme, an autosomal recessive trait, causes lipoamide dehydrogenase deficiency.
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| dihydrolipoyl |
the acyl radical of dihydrolipoamide.
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| dihydrolipoyltransacetylase |
dihydrolipoamide S-acetyltransferase.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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