| IAP | immunosuppressive acidic protein; inosinic acid pyrophosphorylase; Institute of Animal Physiology; i... |
|---|---|
| ILAR | Institute of Laboratory Animal Research |
| LADA | laboratory animal dander allergy; left acromio-dorso-anterior [position]; left anterior descending a... |
| M/A | male, altered [animal]; mood and/or affect |
| MALT | male, altered [animal]; mucosa-associated lymphoid tissue; Munich Alcoholism Test |
| sentinel animal | An animal deliberately placed in a particular environment to detect the presence of an infectious agent, such as a virus. (05 Mar 2000) |
|---|---|
| Houssay animal | An animal that has been pancreatectomised and hypophysectomised. Named after the discoverer of the principle that animal's are more sensitive to insulin after removal of the pituitary, and that after this operation the intensity of diabetes in depancreatised animal's is diminished. (05 Mar 2000) |
| sex behaviour, animal | Sexual activities of animals. (12 Dec 1998) |
| normal animal | In research, an experimental animal that has neither suffered an attack of a particular disease nor received an injection of a specific microorganism or its toxin. (05 Mar 2000) |
| disease models, animal | Animal disease whose pathologic mechanisms are sufficiently similar to those of a different human disease for the animal disease to serve as a model. The animal disease may be either induced or naturally occurring so long as it is not the same clinical entity as the disease for which it serves as a model. E.g., scrapie is an animal model for multiple sclerosis, which has never been found or induced in an animal. (12 Dec 1998) |
| eliminative behaviour, animal | Behaviour associated with the elimination of feces and urine from the body. (12 Dec 1998) |
| toxoplasmosis, animal | Acquired infection of non-human animals by organisms of the genus toxoplasma. (12 Dec 1998) |
| transgenic animal | Genetically engineered animalor offspring of genetically engineeredanimals. The transgenic animal usually contains material from at leaseone unrelated organism, such as from a virus, plant, or other animal. (09 Oct 1997) |
| laboratory animal science | The science and technology dealing with the procurement, breeding, care, health, and selection of animals used in biomedical research and testing. (12 Dec 1998) |
| lameness, animal | A departure from the normal gait in animals. It is also called claudication. (12 Dec 1998) |
| Addison's clinical planes | A series of plane's used as landmarks in thoracoabdominal topography; the trunk is divided vertically by a median plane from the upper border of the manubrium of the sternum to the pubic symphysis, by a lateral plane drawn vertically on either side through a point half way between the anterior superior iliac spine and the median plane at the interspinal plane, and by an interspinal plane passing vertically through the anterior superior iliac spine on either side; transversely the trunk is divided by a transthoracic plane passing across the thorax 3.2 cm above the lower border of the body of the sternum, by a transpyloric plane midway between the jugular notch of the sternum and the pubic symphysis, corresponding to the disc between the first and second lumbar vertebrae, and by an intertubercular plane passing through the iliac tubercles and cutting usually the fifth lumbar vertebra; the plane's formed on these lines, and also on transverse plane's cutting the upper edge of the manubrium and the upper edge of the pubic symphysis, constitute the clinical plane's of Addison. (05 Mar 2000) |
| pathology, clinical | A subspecialty of pathology which deals with the laboratory analysis of specimens of human blood and other fluids. (12 Dec 1998) |
| chemistry, clinical | The specialty of analytical chemistry applied to assays of physiologically important substances found in blood, urine, tissues, and other biological fluids for the purpose of aiding the physician in making a diagnosis or following therapy. (12 Dec 1998) |
| pharmacology, clinical | The branch of pharmacology that deals directly with the effectiveness and safety of drugs in humans. (12 Dec 1998) |
| phase I clinical trial | <pharmacology> The earliest stage clinical trial for studying an experimental drug in humans. Phase I trials are generally comparatively small and are used to determine toxicity and maximum dose. They provide an initial evaluation of a drug's safety and pharmacokinetics-how the drug is absorbed, what tissues it reaches and how long it takes to leave the body. Such studies also usually test various doses of the drug (dose-ranging) to obtain an indication of the appropriate dose to use in later studies. The patients in these trials usually have advanced disease and have already received best available chemotherapy, therefore, seeing a repose is significant partially because this means there is a lack of cross-resistance between two anti-cancer drugs. (31 Dec 1997) |