| bilirubin encephalopathy | <paediatrics> Disorder due to jaundice in a newborn baby with high blood levels of the pigment bilirubin that is deposited in the brain resulting in damage. The level of bilirubin is monitored in newborns to determine whether treatment is needed to prevent kernicterus. With brain affected, it is also called bilirubin encephalopathy. (12 Dec 1998) |
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| bilirubin glucuronoside glucuronosyltransferase | <enzyme> Conjugates one or two glucuronic acid molecules to the carboxyl groups of the propionate side chains of bilirubin thereby removing free bilirubin from the body; ugt1.4 is the minor human bilirubin udp-glucuronosyltransferase (ugt) Registry number: EC 2.4.1.95 Synonym: bilirubin glucuronyl transferase, bilirubin glucuronyltransferase, bilirubin udp-glucuronosyltransferase, ugt1.4 (26 Jun 1999) |
| bilirubin monoglucuronide transglucuronidase | <enzyme> Is a transferase that transfers a glucuronoside from one molecule of bilirubin glucuronoside to another, forming bilirubin bisglucuronoside and unconjugated bilirubin. A step in haem catabolism. (05 May 2002) |
| bilirubin UDP-glucuronyltransferase | <enzyme> An enzyme that catalyses the reaction of UDP-glucuronate and bilirubin forming UDP and bilirubin-glucuronoside; a deficiency of this enzyme is associated with Crigler-Najjar syndrome. (05 Mar 2000) |
| bilirubinaemia | The presence of bilirubin in the blood, where it is normally present in relatively small amounts; the term is usually used in relation to increased concentrations observed in various pathologic conditions where there is excessive destruction of erythrocytes or interference with the mechanism of excretion in the bile. Determination of the quantity of bilirubin in the blood serum reveals two fractions, namely direct reacting (conjugated) and indirect reacting (nonconjugated) bilirubin; determination of conjugated and total bilirubin in serum is an important and frequently used clinical laboratory test. Origin: bilirubin + G. Haima, blood (05 Mar 2000) |
| bilirubinglobulin | A bilirubin-globulin complex; a transport form of bilirubin to the liver where bilirubin is converted to a diglucuronic acid derivative and passes into the bile. (05 Mar 2000) |
| bilirubinoids | <biochemistry> Generic term denoting intermediates in the conversion of bilirubin to stercobilin by reductive enzymes in intestinal bacteria. Included are mesobilirubin, mesobilane mesobilene-b, urobilinogen, urobilin, reduction products of mesobilane (stercobilinogen) and mesobilene (stercobilin), and mesobiliviolin. Most are found in normal urine and faeces. Products related to these intermediates and found in pathological conditions (e.g., jaundice, liver disease) are the structurally indefinite probilifuscins and propentdyopents found in gallstones. (05 Mar 2000) |
| bilirubinuria | The presence of bilirubin in the urine. Origin: bilirubin + G. Ouron, urine (05 Mar 2000) |
| bilitherapy | Treatment with bile or bile salts. (05 Mar 2000) |
| bilitranslocase | <chemical> Plasma membrane protein involved in hepatic bilibubin and organic anion uptake Chemical name: translocase, bilirubin (26 Jun 1999) |
| biliuria | The presence of various bile salts, or bile, in the urine. Synonym: choleuria, choluria. Origin: bili-+ G. Ouron, urine (05 Mar 2000) |
| biliverdin | <biochemistry> A green pigment found in bile which is formed during haem catabolism, mainly the breaking down of old red blood cells, within the liver. It has the chemical formula C33H34N4O6. It transforms into the red-orange bile pigment bilirubin. (09 Oct 1997) |
| biliverdine | <chemical> 1,3,6,7-tetramethyl-4,5-dicarboxyethyl-2,8-divinylbilenone. Biosynthesised from haemoglobin as a precursor of bilirubin. Occurs in the bile of amphibia and of birds, but not in normal human bile or serum. Chemical name: 21H-Biline-8,12-dipropanoic acid, 3,18-diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo- (12 Dec 1998) |
| biliverdinglobin | An obsolete term for choleglobin. (05 Mar 2000) |
| Bill's manoeuvre | Forceps rotation of the foetal head at mid-pelvis before extraction of the head. (05 Mar 2000) |