| aminodeoxychorismate lyase | <enzyme> Catalyses the conversion of aminodeoxychorismate to paba and pyruvate Registry number: EC 4.1.3.- Synonym: enzyme x, folate biosynthesis, 4-amino-4-deoxychorismate pyruvate-lyase (26 Jun 1999) |
|---|---|
| aminodeoxychorismate synthase | <enzyme> From E coli; probably catalyses the conversion of chorismate to 4-amino-4-deoxychorismate; see also paba protein Registry number: EC 2.6.1.- Synonym: pabb gene product, adc synthase (26 Jun 1999) |
| aminoethanoic acid | <amino acid, physiology> The simplest amino acid. It is a common residue in proteins, especially collagen and elastin and is not optically active. It is also a major inhibitory neurotransmitter in spinal cord and brainstem of vertebrate central nervous system. (18 Nov 1997) |
| aminoethylphosphonic acid | <chemical> (2-aminoethyl)-phosphonic acid. An organophosphorus compound isolated from human and animal tissues. Chemical name: Phosphonic acid, (2-aminoethyl)- (12 Dec 1998) |
| aminoglutethimide | <chemical> An aromatase inhibitor that produces a state of "medical" adrenalectomy by blocking the production of adrenal steroids. It also blocks the conversion of androgens to oestrogens. Aminoglutethimide has been used in the treatment of advanced breast and prostate cancer. It was formerly used for its weak anticonvulsant properties. Pharmacological action: adrenergic agents, antineoplastic agent, hormonal, enzyme inhibitors. Chemical name: 2,6-Piperidinedione, 3-(4-aminophenyl)-3-ethyl- (12 Dec 1998) |
| aminoglycoside | <pharmacology> A group of antibiotics active against many aerobic gram-negative and some gram-positive bacteria. They are mostly produced by fungi and contain an amino sugar, and amino-or guanido-substituted inositol ring which are attached by a glycosidic linkage to a hexose nucleus resulting in a polycationic and highly polar compound. They inhibit bacterial protein synthesis by binding to a site on the 30S ribosomal subunit thereby altering codon anticodon recognition. They are all broad-spectrum antibiotics and can cause renal toxicity and ototoxicity. Common examples are streptomycin, gentamicin, amikacin, kanamycin, tobramycin, netilmicin, neomycin, framycetin. (13 Oct 1997) |
| aminoglycoside 3'-phosphotransferase | <enzyme> A bacterial enzyme which confers resistance to the antibiotic neomycin.The APH gene is used as a selectable marker in genetic experiments, whereby bacterial cells which do not have the gene are eliminated from a population and thus selected against when exposed to neomycin. (13 Oct 1997) |
| aminoglycoside 6-adenylyltransferase | <enzyme> From bacillus subtilis marburg Registry number: EC 2.7.7.- Synonym: aminoglycoside 6-adenyltransferase, ag-6-atransferase (26 Jun 1999) |
| aminoglycoside acetyltransferase | <enzyme> See also gentamicin acetyltransferase Registry number: EC 2.3.1.- Synonym: aminocyclitol acetyltransferase, neomycin acetyltransferase (26 Jun 1999) |
| aminoglycoside N(3')-acetyltransferase | <enzyme> Catalyses the reaction of CoA and acetyl-2-deoxystreptamine antibiotic to yield acetyl-CoA and a 2-deoxystreptamine antibiotic; has broad specificity; acts on gentamicin, tobramycin, sisomicin, netilmicin, kanamycin, neomycin and apramycin Registry number: EC 2.3.1.81 Synonym: aac(3)-iv, aminoglycoside-(3)-n-acetyltransferase iv (26 Jun 1999) |
| aminoglycoside N(6')-acetyltransferase | <enzyme> The antibiotic kanamycin, gentamicin, tobramycin, and neomycin can act as an acceptor; has to be 6'-acetyltransferase Registry number: EC 2.3.1.82 Synonym: amikacin acetyltransferase, aminoglycoside-6'-n-acetyltransferase, gentamicin 6'-acetyltransferase, 6' gat gene product, aac(6') (26 Jun 1999) |
| aminoglycoside N1-acetyltransferase | <enzyme> Monoacetylates apramycin, butirosin, lividomycin and paromomycin at the c1 amino group and diacetylates ribostamycin and neomycin, at the c1 amino and possibly at the 6' amino group Registry number: EC 2.3.1.- Synonym: acc1 enzyme, paromomycin acetyltransferase (26 Jun 1999) |
| aminoglycoside phosphoribosyltransferase | <enzyme> Coded by neo-gene; involved in kanamycin resistance; no other information given on reaction 8/93 Registry number: EC 2.4.2.- Synonym: aminoglycosidephosphoribosyltransferase (26 Jun 1999) |
| aminohippuric acids | A group of glycine amides of aminobenzoic acids. (12 Dec 1998) |
| aminohydrolases | <enzyme> Registry number: EC 3.5.4. (12 Dec 1998) |
Synonyms : Amino Acid, Acidic, Acidic Amino Acid
Synonyms : Amino Acid, Aromatic, Aromatic Amino Acid
Synonyms : Basic Amino Acid, Amino Acid, Basic
Synonyms : Amino Acids, Branched Chain, Acids, Branched-Chain Amino, Branched-Chain Amino Acids
Synonyms : Acids, Cyclic Amino
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