| EPF | early pregnancy factor; endocarditis parietalis fibroplastica; endothelial proliferating factor; est... |
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| HF | Hageman factor; haplotype frequency; hard filled [capsule]; hay fever; head of fetus; head forward; ... |
| IF | idiopathic fibroplasia; idiopathic flushing; immersion foot; immunofluorescence; indirect fluorescen... |
| KAF | conglutinogen-activating factor; killer-assisting factor; kinase activating factor |
| LEF | leukokinesis-enhancing factor; lupus erythematosus factor; lymphoid-enhanced binding factor |
| Frerichs, Friedrich von | <person> German pathologist and clinician, 1819-1885. See: Frerichs' theory. (05 Mar 2000) |
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| Frey, Max von | <person> German physician, 1852-1932. See: Frey's hairs. (05 Mar 2000) |
| Lenhossek, Michael von | <person> Hungarian anatomist, 1863-1937. See: Lenhossek's processes. (05 Mar 2000) |
| Leydig, Franz von | <person> In 1855 was appointed Professor of Histology in Wurzburg and later in Tubingen and Bonn. Was the founder of Comparative Histology. Leydig's Cells - interstitial cells of the testis. Lived: 1821-1908. B. Rothenburg, May 21st, 1821, d. Apr 13th, 1908. (05 Dec 1998) |
| Liebermann, Leo von | <person> Hungarian physician, 1852-1926. See: Burchard-Liebermann reaction, Liebermann-Burchard test. (05 Mar 2000) |
| Liebermeister, Carl von | <person> German physician, 1833-1901. See: Liebermeister's rule. (05 Mar 2000) |
| Liebig, Baron Justus von | <person> German chemist, 1803-1873. See: Liebig's theory. (05 Mar 2000) |
| lindau-von hippel syndrome | <syndrome> The cardinal features of what is more commonly called von hippel-lindau (vhl) syndrome are benign blood-vessel tumours that most typically affect the eye and the brain. The eye tumours are termed angiomata and are in the retina. The brain tumours are termed haemangioblastoma and are in the cerebellum. Vhl is complex. There can also be blood-vessel tumours (haemangiomata) in the spinal cord, adrenal glands, liver, and lungs. Pheochromocytoma (a benign tumour of adrenal-like tissue) occurs in some patients. The combination of high blood pressure (hypertension) with angioma may cause bleeding under the skull (subarachnoid haemorrhage). Kidney tumours (like hypernephromas) may be malignant and metastasize. An abnormal elevation of red blood cells (polycythemia) can be due to the haemangioblastoma of the cerebellum or the hypernephroma. Multiple cysts can occur in the pancreas and kidneys. Patients with kidney problems or pancreatic cysts do not have pheochromocytoma, and visa versa. Lab findings in vhl may include high calcium (hypercalcaemia) and low potassium (hypokalaemia) occurring with the pheochromocytoma. Vhl is inherited as an autosomal dominant trait. The gene on one of the non-sex chromosomes is dominant over the normal gene with which it is paired so that one vhl gene is sufficient to cause the vhl syndrome. If a person has vhl, the chance for each of their children to receive the vhl gene is one-half (50%). The vhl gene has been mapped to chromosome 3 (the 3rd volume in the book of life) in region 3p26-p25. The vhl gene has the characteristics of a tumour-suppressor gene. The person with vhl inherits one inactive copy of the vhl gene (a germline mutation) from one of their parents. But the normal gene with which it is paired is still enough to suppress the formation of a tumour. Then, in one cell in the vhl patient's body, another mutation (a somatic mutation) occurs, inactivating the other vhl gene. Thus, both copies of the vhl gene are inactivated and a tumour arises in the vhl patient. The syndrome is named for the german ophthalmologist eugen von hippel who described the charcteristic eye blood-vessel tumours in 1904 and the swedish pathologist arvid lindau who recognised the association between the eye tumours and the blood-vessel tumours of the cerebellum and other parts of the central nervous system in 1926-7. (12 Dec 1998) |
| Ludwig, Wilhelm Friedrich von | <person> German surgeon, 1790-1865. See: Ludwig's angina. (05 Mar 2000) |
| accelerator factor | <chemical> Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor v accomplishes this by forming a complex with factor xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor v leads to owren's disease. Chemical name: Blood-coagulation factor V (12 Dec 1998) |
| acetate replacement factor | <biochemistry> 1,2 dithiolane 3 valeric acid. Regarded as a coenzyme in the oxoglutarate dehydrogenase complex of the citric acid cycle. Involved generally in oxidative decarboxylations of _ keto acids. A growth factor for some organisms. (18 Nov 1997) |
| adrenal weight factor | A postulated substance of adenohypophysial origin responsible for maintenance of the weight of the adrenal cortex. (05 Mar 2000) |
| adrenocorticotropic releasing factor | Hormone produced by hypothalamus that causes pituitary to secrete adrenocorticotropic hormone. (05 Mar 2000) |
| a-factor | <molecular biology> A protein which is found in the bacterial genus Streptomyces that helps start the production of streptomycin and the process of morphological differentiation. It is used in biotechnology to induce these functions in mutant strains of Streptomyces that cannot produce it themselves. (09 Feb 1998) |
| angiogenesis factor | Substance causing proliferation of new blood vessels. It is found in tissues with high metabolic requirements, such as the retina, and in certain cancers. The factor is also released by hypoxic macrophages at the edges or outer surfaces of wounds and initiates revascularization in wound healing. (12 Dec 1998) |