| tumour specific antigen | <immunology, oncology> Antigen on tumour cells detected by cell-mediated immunity. For virus transformed cells TSTA (unlike T antigen) is found to differ for different individual tumours induced by the same virus. May consist of fragments of T antigens exposed at the cell surface. (18 Nov 1997) |
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| tumour-specific transplantation antigens | Surface antigen's of DNA tumour virus-transformed cells, which elicit an immune rejection of the virus-free cells when transplanted into an animal that has been immunised against the specific cell-transforming virus. (05 Mar 2000) |
| uridine-specific acid nuclease | <enzyme> Chicken liver enzyme hydrolyzes poly(u) and e. Coli RNA Registry number: EC 3.1.- (26 Jun 1999) |
| fluoroacetate-specific dehalogenase | <enzyme> Acts on fluoroacetamide at 0.1 the rate for fluoroacetate Registry number: EC 3.8.1.- Synonym: fluoroacetate-specific defluorinase, fac dehalogenase (26 Jun 1999) |
| law of specific nerve energies | Each type of sensory nerve ending, however stimulated (electrically, mechanically, etc.), gives rise to its own specific sensation; moreover, each type of sensation depends not upon any special character of the different nerves but upon the part of the brain in which their fibres terminate. Synonym: law of specific nerve energies. (05 Mar 2000) |
| lymphocyte specific protein tyrosine kinase p56(lck) | <enzyme> This enzyme is a lymphoid specific src family tyrosine kinase that is critical for T-cell development and activation. Lck is associated with the cytoplasmic domains of CD4, CD8 and the beta-chain of the il-2 receptor, and is thought to be involved in the earliest steps of tcr-mediated T-cell activation. Registry number: EC 2.7.11.- (12 Dec 1998) |
| acrocephalosyndactyly type 1 | <paediatrics> An inherited disease (autosomal dominant) or a spontaneously occurring disease characterised by a peaked head and unusual facial appearance, due to the premature closure of the cranial sutures. A skull X-ray can confirm the diagnosis and treatment is surgical. Inheritance: autosomal dominant. (27 Sep 1997) |
| Alzheimer type I astrocyte | Enlarged frequently multinucleated astrocytes, seen in progressive multifocal leukoencephalopathy. (05 Mar 2000) |
| Alzheimer type II astrocyte | Enlarged astrocytes with vesicular nuclei and one or more small basophilic nucleoli, seen in hepatocerebral disease and Wilson's disease. (05 Mar 2000) |
| American Type Culture Collection | <cell culture> A key resource for cultured cells, located in Rockville, USA. (12 Dec 1998) |
| Antoni type A neurilemoma | <tumour> Relatively solid or compact arrangement of neoplastic tissue that consists of Schwann cells arranged in twisting bundles and associated with delicate reticulin fibres; the nuclei of the Schwann cells are frequently grouped in parallel rows (so-called palisades), and the nuclei and fibres sometimes form exaggerated tactile corpuscles, called Verocay bodies. (05 Mar 2000) |
| Antoni type B neurilemoma | <tumour> Relatively soft or loose arrangement of neoplastic tissue that consists of Schwann cells in a haphazard or nondescript type of arrangement among reticulin fibres and tiny cystlike foci; fat-laden macrophages may be observed in some of the larger neoplasms. (05 Mar 2000) |
| arthus-type reaction's | Reaction's in man and other species that result from the same basic immunologic (allergic) mechanism which evokes, in the rabbit, the typical Arthus phenomenon. See: immune complex disease. (05 Mar 2000) |
| avian adenovirus type 1 proteinase | <enzyme> 206 aa residues of which 66% are homologous to human ad2 emzyme embl/genbank l13161 Registry number: EC 3.4.22.- Synonym: aavl proteinase, aavl endopeptidase (26 Jun 1999) |
| basic personality type | An individual's unique, covert, or underlying personality propensities, whether or not they are behaviourally manifest or overt, personality characteristics of an individual which are also shared by a majority of the members of a social group. (05 Mar 2000) |