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specific transduction Transduction in which the bacteriophage strain is able to transfer only some, or only one, of the donor bacterium genes.
Synonym: specific transduction.
(05 Mar 2000)
specific urethritis An obsolete term for gonorrhoea.
(05 Mar 2000)
N(2),N(2)-dimethylguanosine-specific tRNA methyltransferase <enzyme> Responsible for the modification of both mitochondrial and cytoplasmic trnas
Registry number: EC 2.1.1.-
Synonym: dmg trna methyltransferase
(26 Jun 1999)
sporulation-specific cell wall hydrolase <enzyme> From bacillus subtilis; 255-amino acid protein mw 27.146 kD; hydrolyzes both vegetative cell walls and spore peptidoglycan genbank d14666
Registry number: EC 3.-
Synonym: cwlc gene product
(26 Jun 1999)
non-specific 1. Not due to any single known cause, as to a particular pathogen.
2. Not directed against a particular agent, but rather having a general effect, as non-specific therapy.
(18 Nov 1997)
non-specific anergy A reduction of the normal or usual immunologic responses because of unrelated intervening disease.
Synonym: non-specific anergy.
(05 Mar 2000)
non-specific cholinesterase <enzyme> An enzyme that breaks down acetylcholine tostop its action.
(22 May 1997)
non-specific protein A protein substance that elicits a response not mediated by specific antigen-antibody reaction.
(05 Mar 2000)
non-specific system <physiology> A physiological term denoting that part of the brainstem reticular formation that plays a central role in the organism's bodily and behavorial alertness.
It extends as a diffusely organised neural apparatus through the central region of the brainstem into the subthalamus and the intralaminar nuclei of the thalamus; by its ascending connections it affects the function of the cerebral cortex in the sense of behavioural responsiveness; its descending (reticulospinal) connections transmit its activating influence upon bodily posture and reflex mechanisms (e.g., muscle tonus), in part by way of the gamma motor neurons.
See: reticular formation.
Synonym: non-specific system.
(05 Mar 2000)
non-specific therapy The injection of a foreign protein, typhoid vaccine, etc., to induce fever in the treatment of certain diseases, especially those of a parasyphilitic nature.
Synonym: phlogotherapy.
(05 Mar 2000)
non-specific urethritis Urethritis not resulting from gonococcal, chlamydial, or other specific infectious agents.
Synonym: simple urethritis.
(05 Mar 2000)
non-specific vaginitis bacterial vaginosis
sugar-non-specific nuclease <enzyme> An exocytoplasmic sugar-non-specific nuclease that is able to degrade linear or covalently closed circular double-stranded DNA as well as single-stranded DNA or RNA; from cyanobacterium anabaena; mw 29 kD; amino acid sequence has been determined
Registry number: EC 3.1.-
Synonym: nuca gene product, anabaena
(26 Jun 1999)
deoxyribonucleases, type III site-specific <enzyme> Enzyme systems composed of two subunits and requiring ATP and magnesium for endonucleolytic activity; they do not function as atpases. They exist as complexes with modification methylases of similar specificity.
The systems recognise specific short DNA sequences and cleave a short distance, about 24 to 27 bases, away from the recognition sequence to give specific double-stranded fragments with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity are called isoschizomers.
Registry number: EC 3.1.21.5
(12 Dec 1998)
deoxyribonucleases, type II site-specific <enzyme> Enzyme systems containing a single subunit and requiring only magnesium for endonucleolytic activity. The corresponding modification methylases are separate enzymes. The systems recognise specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition sequence to give specific double-stranded fragments with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity are called isoschizomers.
Registry number: EC 3.1.21.4
(12 Dec 1998)
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