| HF | Hageman factor; haplotype frequency; hard filled [capsule]; hay fever; head of fetus; head forward; ... |
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| IF | idiopathic fibroplasia; idiopathic flushing; immersion foot; immunofluorescence; indirect fluorescen... |
| KAF | conglutinogen-activating factor; killer-assisting factor; kinase activating factor |
| LEF | leukokinesis-enhancing factor; lupus erythematosus factor; lymphoid-enhanced binding factor |
| LIF | laser-induced fluorescence; left iliac fossa; left index finger; leukemia-inhibiting factor; leukocy... |
| thyrotoxic serum | An antiserum obtained by injecting into animals the nucleoproteins of the thyroid gland. (05 Mar 2000) |
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| equine serum hepatitis | <veterinary> An acute hepatic disease of the horse, often associated with prior administration of biological products; neurologic signs and jaundice are usually prominent signs; aetiology is unknown. Synonym: Theiler's disease. (05 Mar 2000) |
| truth serum | Colloquialism for a drug, such as amobarbital sodium or thiopental sodium, intravenously injected for the purpose of eliciting information from the subject under its influence; a misnomer because the subject's revelations may or may not be factually true, and its legal status and use is questionable. (05 Mar 2000) |
| foetal calf serum | <cell culture> The serum originating from embryonic calves and an expensive component of standard culture media for many types of animal tissue cells. It is used as an important part of growth media for promoting the growth of tissue cultures. It provides a source of growth hormones and other growth factors. (11 Nov 1997) |
| foreign serum | A serum derived from an animal and injected into an animal of another species or into humans. (05 Mar 2000) |
| liquid human serum | The pool of fluids separated from blood withdrawn from human subjects and allowed to clot in the absence of any anticoagulant; not more than 10 separate donations are pooled; the contributions from donors of A, O, and either B or AB groups are represented in approximately the ratio 9:9:2. (05 Mar 2000) |
| acetone-insoluble antigen | A diphosphatidyl glycerol that is found in the membrane of Treponema pallidum and is the antigen detected by the Wasserman test for syphilis. (18 Nov 1997) |
| allogeneic antigen | Genetic variations of the same antigens within a given species. (05 Mar 2000) |
| antigen | Virus coded cell surface antigens that appear soon after the infection of a cell by virus, but before virus replication has begun. See: early gene. (18 Nov 1997) |
| antigen-antibody complex | The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage causes immune complex diseases. If the antigen is polyvalent the complex may be insoluble. Immune complexes activate complement through the classical pathway. See: glomerulonephritis, Arthus reaction, type III hypersensitivity. (12 Dec 1998) |
| antigen-antibody reaction | The phenomenon, occurring in vitro or in vivo, of antibody combining with antigen of the type that stimulated the formation of the antibody, thereby resulting in agglutination, precipitation, complement fixation, greater susceptibility to ingestion and destruction by phagocytes, or neutralization of exotoxin. See: skin test. (05 Mar 2000) |
| antigen-binding site | <immunology> In immune network theory, an idiotope, an antigenic site of an antibody that is responsible for that antibody binding to an antigenic determinant (epitope). Also used of the site on a ligand molecule to which a cell surface receptor binds. (18 Nov 1997) |
| antigen-combining site | See: paratope. (05 Mar 2000) |
| antigen excess | In a precipitation test, the presence of uncombined antigen above that required to combine with all of the antibody; precipitation may be inhibited because the presence of excess antigen gives rise to soluble antigen-antibody complexes, in vivo the resultant antigen-antibody interaction in such an antigen excess may give rise to immune complexes, which have a potential to induce cellular damage; such injury underlies the pathologic changes seen in certain immune complex diseases. (05 Mar 2000) |
| antigen interferon | <cytokine> Interferon elaborated by T lymphocytes in response to either specific antigen or mitogenic stimulation. This type II interferon can be produced by recombinant DNA technology and is similar to the interferon secreted by lymphocytes and has antiviral and antineoplastic activity. Synonym: antigen interferon, immune interferon. Pharmacological action: antineoplastic agent, antiviral agents. (20 Sep 2002) |