| secondary hypogammaglobulinaemia | Immunodeficiency in which there is no evident defect in the lymphoid tissues, but rather hypercatabolism or loss of immunoglobulins such as occurs in familial idiopathic hypercatabolic hypoproteinaemia or in defects associated with the nephrotic syndrome. Synonym: secondary agammaglobulinaemia, secondary antibody deficiency, secondary hypogammaglobulinaemia. (05 Mar 2000) |
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| secondary hypogonadism | Defective gonadal development or function, or both, resulting from inadequate secretion of pituitary gonadotropins. Synonym: hypogonadotropic eunuchoidism, secondary hypogonadism. (05 Mar 2000) |
| secondary hypothyroidism | Hypothyroidism that arises as a consequence of inadequate thyrotropin secretion by the anterior pituitary gland. (05 Mar 2000) |
| secondary immune response | The response of the immune system to the second or subsequent occasion on which it encounters a specific antigen. (18 Nov 1997) |
| secondary immunodeficiency | Immunodeficiency in which there is no evident defect in the lymphoid tissues, but rather hypercatabolism or loss of immunoglobulins such as occurs in familial idiopathic hypercatabolic hypoproteinaemia or in defects associated with the nephrotic syndrome. Synonym: secondary agammaglobulinaemia, secondary antibody deficiency, secondary hypogammaglobulinaemia. (05 Mar 2000) |
| secondary infection | An infection, usually septic, occurring in a person or animal already suffering from an infection of another nature. (05 Mar 2000) |
| secondary interatrial foramen | A secondary opening appearing in the upper part of the septum primum in the sixth week of embryonic life, just prior to the closure of the interatrial foramen primum. Synonym: ostium secundum, secondary interatrial foramen. (05 Mar 2000) |
| secondary leukaemia | A leukaemia arising from either previous chemotherapy or radiotherapy or as the development of a pre-existing condition, such as myelodysplasia. Origin: Gr. Haima = blood (13 Nov 1997) |
| secondary lung cancer | The spread of cancerous tumours from a distant organ to the lung. Due to the lungs tremendous blood and lymphatic supply it is a frequent site for metastatic cancer. Cancers which commonly metastasize to the lung include osteosarcoma, breast cancer, neuroblastoma, Wilm's tumour and non-Hodgkin's lymphomas. (27 Sep 1997) |
| secondary lymphoid tissue | <anatomy> Tissue that is particularly rich in lymphocytes (and accessory cells such as macrophages and reticular cells), particularly the lymph nodes, spleen, thymus, Peyer's patches, pharyngeal tonsils, adenoids and (in birds) the Bursa of Fabricius. Central lymphoid tissue: A term occasionally used as synonym for primary lymphoid tissue but should be avoided to prevent confusion between anatomical location, which is irrelevant and centrality in the system. Peripheral lymphoid tissue: Secondary lymphoid tissue, not necessarily located peripherally. Primary lymphoid tissue: Lymphoid tissues in which immune cells develop as opposed to the secondary or peripheral lymphoid tissues in which antigen independent or antigen dependent stages of maturation take place and in which responsive lymphocytes are found. Primary lymphoid tissues are foetal liver, adult bone marrow and thymus (and Bursa of Fabricius in birds). Secondary tissues are lymph nodes, spleen, tonsils and mucosa associated lymphoid tissue. (20 Mar 1998) |
| secondary lysosome | <cell biology> Term used to describe intracellular vacuoles formed by the fusion of lysosomes with organelles (autosomes) or with primary phagosomes. Residual bodies are the remnants of secondary lysosomes containing indigestible material. Origin: Gr. Soma = body (18 Nov 1997) |
| secondary lysosomes | Lysosome's in which lysis takes place, owing to the activity of hydrolytic enzymes; they are believed to eventually become residual bodies. Synonym: definitive lysosomes, digestive vacuole. (05 Mar 2000) |
| secondary medical care | Medical care by a physician who acts as a consultant at the request of the primary physician. (05 Mar 2000) |
| secondary megaureter | Hydroureter secondary to vesicoureteral reflux or distal obstruction. (05 Mar 2000) |
| secondary mesoderm | Mesoderm derived from the primitive streak and lying between the ectoderm and endoderm. Synonym: secondary mesoderm. (05 Mar 2000) |