| zygotic effect gene | <genetics> A gene whose phenotype is dependent on the genotype of the zygote, rather than the genotype of the mother. See: maternal effect gene. (18 Nov 1997) |
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| late effect | Side effects of chemotherapy and/or radiotherapy which only become apparent with long-term monitoring of the patient over a period of years. These are of particular concern in patients below the age of puberty. (18 Nov 1997) |
| founder effect | The establishment of a new population by a few original founders (in an extreme case, by a single fertilized female) which carry only a small fraction of the total genetic variation of the parental population [Ernst Mayr, 1963]. The result is that a given allele, gene, chromosome, or part of a chromosome found in members of the population can be traced back to one ancestral individual. (09 Oct 1997) |