Oligonucleotide Probes - ț̢
Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin.
Oligonucleotides - ț̢
Polymers made up of a few (2-20) nucleotides. In molecular genetics, they refer to a short sequence synthesized to match a region where a mutation is known to occur, and then used as a probe (OLIGONUCLEOTIDE PROBES). (Dorland, 28th ed)
Synonyms :
Oligonucleotides, Antisense - ț̢
Short fragments of DNA or RNA that are used to alter the function of target RNAs or DNAs to which they hybridize.
Synonyms : Anti-Sense Oligonucleotides, Anti Sense Oligonucleotides, Oligonucleotides, Anti-Sense
Oligopeptides - ț̢
Peptides composed of between two and twelve amino acids.
Synonyms :
Oligoribonucleotides - ț̢
A group of ribonucleotides (up to 12) in which the phosphate residues of each ribonucleotide act as bridges in forming diester linkages between the ribose moieties.