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MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 7
  • Nucleic Acid Denaturation - »õâ Disruption of the secondary structure of nucleic acids by heat, extreme pH or chemical treatment. Double strand DNA is "melted" by dissociation of the non-covalent hydrogen bonds and hydrophobic interactions. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible.
    Synonyms : Acid Denaturation, Nucleic, Denaturation, DNA, Denaturation, Nucleic Acid, Denaturation, RNA, Nucleic Acid Denaturations
  • Nucleic Acid Heteroduplexes - »õâ Double-stranded nucleic acid molecules (DNA-DNA or DNA-RNA) which contain regions of nucleotide mismatches (non-complementary). In vivo, these heteroduplexes can result from mutation or genetic recombination; in vitro, they are formed by nucleic acid hybridization. Electron microscopic analysis of the resulting heteroduplexes facilitates the mapping of regions of base sequence homology of nucleic acids.
    Synonyms : Heteroduplex DNA, Acid Heteroduplexes, Nucleic, DNA, Heteroduplex
  • Nucleic Acid Hybridization - »õâ Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
    Synonyms : Acid Hybridization, Nucleic, Acid Hybridizations, Nucleic, Genomic Hybridizations, Hybridization, Genomic, Hybridization, Nucleic Acid, Hybridizations, Genomic, Hybridizations, Nucleic Acid, Nucleic Acid Hybridizations
  • Nucleic Acid Precursors - »õâ Use for nucleic acid precursors in general or for which there is no specific heading.
    Synonyms : Acid Precursors, Nucleic, Precursors, Nucleic Acid
  • Nucleic Acid Probes - »õâ Nucleic acid which complements a specific mRNA or DNA molecule, or fragment thereof; used for hybridization studies in order to identify microorganisms and for genetic studies.
    Synonyms : Acid Probes, Nucleic, Probes, Nucleic Acid
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MeSH(Medical Subject Headings) À¯»ç °Ë»ö (http://www.nlm.nih.gov) °á°ú : 0 ÆäÀÌÁö: 7
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