| Schede's method | Filling of the defect in bone, after removal of a sequestrum or scraping away carious material, by allowing the cavity to fill with blood which may become organised (Schede's clot). (05 Mar 2000) |
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| Schick method | A test for susceptibility to Corynebacterium diphtheriae toxin: 0.1 ml of Schick test toxin is injected into the skin of one forearm (test site) and the same quantity of the same, but heat-inactivated, material into the skin of the other forearm (control site); individuals with toxin-neutralizing antibodies either will have no reaction at either injection site (negative test) or may have a pseudoreaction due to antibodies for substances (antigens) in the test materials other than diphtheria toxin; individuals lacking toxin-neutralizing antibodies may have a positive reaction, which consists of an area of redness appearing 24 to 36 hours at the test site only and persisting for 4 to 5 days. Synonym: Schick method. (05 Mar 2000) |
| schlieren method | <radiobiology> An optical technique that detects density gradients occuring in a fluid flow. In its simplest form, light from a slit is collimated by a lens and focused onto a knife edge by a second lens, the flow pattern is placed between the two lenses, and the resulting diffraction pattern is observed on a screen or photographic film placed behind the knife edge. (09 Oct 1997) |
| Schmidt-Thannhauser method | A method for fractionation of nucleic acid, based upon the fact that RNA but not DNA is hydrolyzed to nucleotides by alkali; RNA can be hydrolyzed in about 2 hours in 0.75 n NaOH, but 18 hours and 0.3 n NaOH usually are used. (05 Mar 2000) |
| Schweninger's method | A method suggested to reduce obesity by restricting intake of fluid. (05 Mar 2000) |
| scientific method | The universally-accepted, organised approach to the study of science, which consists of the following steps: 1. Observation - collecting data. 2. Hypothesis - forming a preliminary possible explanation of the data. 3. Testing - test the hypothesis by collecting more data. 4. Results - interpreting the results of the test and deciding if the hypothesis should be rejected. The hypothesis is rejected if the results contradict it, showing that it is wrong. 5. Conclusion - stating a conclusion that can be evaluated independently by others. (09 Oct 1997) |
| hexokinase method | The most specific method for measuring glucose in serum or plasma, wherein hexokinase plus ATP transforms glucose to glucose-6-phosphate plus ADP; glucose-6-phosphate is then reacted with NADP and glucose-6-phosphate dehydrogenase to form NADP which is measured spectrophotometrically. (05 Mar 2000) |
| Hilton's method | Division of the nerves supplying a part, for the relief of pain in ulcers. (05 Mar 2000) |
| Hirschberg's method | A method of measuring the amount of deviation of a strabismic eye, by observing the reflection of a light fixated by the straight eye on the cornea of the deviating eye. (05 Mar 2000) |
| Purmann's method | Treatment of aneurysm by extirpation of the sac. (05 Mar 2000) |
| Hung's method | A simple saline flotation method for concentrating helminth eggs in the faeces. See: flotation method. Synonym: Hung's method. (05 Mar 2000) |
| Shaffer-Hartmann method | An obsolete method for the quantitative determination of glucose in biological fluids, based on the reduction of copper by the reducing group of the sugar. (05 Mar 2000) |
| shotgun method | Cloning of DNA fragments randomly generated from a genome. See: genomic library. (09 Oct 1997) |
| single-blind method | A method in which either the observer(s) or the subject(s) is kept ignorant of the group to which the subjects are assigned. (12 Dec 1998) |
| Somogyi method | A measure of the level of activity of amylase in blood serum, as analyzed by means of the Somogyi method (the most frequently used procedure); one unit is equivalent to 1 mg of reducing sugar liberated as glucose per 100 ml of serum, when an aliquot of the latter is mixed with a standard starch substrate (plus sodium chloride for maximal activation) and incubated for a standard time; normal range is 80 to 150 unit's, but values are usually not regarded as clinically significant unless they are greater than 200. (05 Mar 2000) |