| methylmalonic acidaemia | <biochemistry> A group of inherited metabolic disorders that result in the accumulation of methylmalonic acid in the bloodstream. This leads to a severe metabolic acidosis (and ketosis) that can be fatal. A defect in the metabolic pathway of methylmalonic acid, vitamin B12 and succinic acid is the underlying cause. An infection can trigger a bout of acidosis. A low protein diet is essential in these patients. Occasionally large doses of vitamin B12 or an alkalinising agent (bicarbonate) will be necessary to treat acute exacerbations of acidosis. Origin: Gr. Haima = blood (27 Sep 1997) |
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| methylmalonic acidemia | ketotic hyperglycinaemia |
| methylmalonic aciduria | Excretion of excessive amounts of methylmalonic acid in urine owing to deficient activity of methylmalonyl-CoA mutase or deficient cobalamin reductase. Two types occur: 1) an inborn error of metabolism resulting in severe ketoacidosis shortly after birth, with long-chain urinary ketones; autosomal recessive inheritance; 2) acquired, a type due to vitamin B12 deficiency due to defective synthesis of adenosylcobalamin. (05 Mar 2000) |
| methylmalonyl-CoA | An intermediate in the degradation of several metabolites (e.g., valine, methionine, odd-chain fatty acids, theronine); elevated in cases of pernicious anaemia. (05 Mar 2000) |
| methylmalonyl-CoA epimerase | <enzyme> An enzyme that catalyses the interconversion of d-methylmalonyl-CoA and l-methylmalonyl-CoA. (05 Mar 2000) |
| methylmalonyl-CoA mutase | <enzyme> An enzyme that catalyses the conversion of methylmalonyl-CoA to succinyl-CoA by transfer of the carbonyl group. It requires a cobamide coenzyme. A block in this enzymatic conversion leads to the metabolic disease, methylmalonic aciduria. Chemical name: (R)-2-Methyl-3-oxopropanoyl-CoA CoA-carbonylmutase Registry number: EC 5.4.99.2 (12 Dec 1998) |
| methylmannosides | Mannosides formed by the reaction of the hydroxyl group on the anomeric carbon atom of mannose with methyl alcohol. They include both alpha- and beta-methylmannosides. (12 Dec 1998) |
| methylmercury | A contaminant of seafood products synthesised in sediments from mercury and mercury-containing chemicals dumped in waters supporting marine life. The methylmercury is concentrated in aquatic life forms and can thus be deposited in fishes intended for human consumption. Probable cause of Minimata disease, a teratogenic condition characterised by multiple birth defects. An inorganic reagent. See: Minamata disease. Synonym: methylmercury. (05 Mar 2000) |
| methylmercury compounds | Organic compounds in which mercury is attached to a methyl group. (12 Dec 1998) |
| methylmethacrylates | The methyl esters of methacrylic acid that polymerise easily and are used as tissue cements, dental materials, and absorbent for biological substances. (12 Dec 1998) |
| methylmorphine | <chemical> An opioid analgesic related to morphine but with less potent analgesic properties and mild sedative effects. It also acts centrally to suppress cough. Pharmacological action: analgesics, opioid, antitussive agents, narcotics. Chemical name: Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)- (12 Dec 1998) |
| methylnitronitrosoguanidine | <chemical> 1-methyl-3-nitro-1-nitrosoguanidine. A nitrosoguanidine derivative with potent mutagenic and carcinogenic properties. Pharmacological action: carcinogens, mutagens. Chemical name: Guanidine, N-methyl-N'-nitro-N-nitroso- (12 Dec 1998) |
| methylnitrosourea | <chemical> 1-methyl-1-nitrosourea. A nitrosourea compound with alkylating, carcinogenic, and mutagenic properties. Pharmacological action: alkylating agents, carcinogens, mutagens. Chemical name: Urea, N-methyl-N-nitroso- (12 Dec 1998) |
| methylococcaceae | A family of gram-negative, aerobic bacteria utilizing only one-carbon organic compounds. (12 Dec 1998) |
| methylol | Hydroxymethyl; the radical, -CH2OH. (05 Mar 2000) |
Synonyms : Propionyl-Coenzyme A Carboxylase, Carboxylase, Propionyl-Coenzyme A, Decarboxylase, Methylmalonyl-CoA, Methylmalonyl CoA Decarboxylase, Propionyl CoA Carboxylase, Propionyl Coenzyme A Carboxylase
Synonyms : Isomerase, Methylmalonyl-CoA, Methylmalonyl CoA Isomerase, Methylmalonyl CoA Mutase, Mutase, Methylmalonyl-CoA
Synonyms :
Synonyms : Compounds, Methyl Mercury, Compounds, Methylmercury, Mercury Compounds, Methyl
Synonyms : Cranioplast, Kallocryl, Kallocryl A, Metaplex, Methacrylate Methyl Monomer, Simplex P, Sintex, Zimmer Bone Cement, A, Kallocryl, Bone Cement, Zimmer, Cement, Zimmer Bone, Methyl Monomer, Methacrylate, Methyl Monomer, Methylmethacrylate, Monomer, Methacrylate Methyl
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| methyl bromide |
the gaseous compound CH3Br used primarily as an insect fumigant; found to be harmful to the stratospheric ozone layer which protects life on earth from excessive ultraviolet radiation.
Ãâó: www.nrdc.org/reference/glossary/m.asp
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| methylation |
The addition of a chemical group (methyl) to DNA that epigenentically alters gene expression.
Ãâó: plan2005.cancer.gov/glossary.html
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| methylcobalamin |
An active form of B12. Vitamin B12 comes in several forms, but only the methyl form is used in the central nervous system. Cyanocobalamin (the form used in vitamin supplements) is converted by the liver into methylcobalamin, but not in therapeutically significant amounts. Vitamin B12 deficiency is caused by a wide range of factors including low gastric acidity, excessive laxative use, poor absorption from the intestines, lack of calcium, and heavy metal toxicity. ...
Ãâó: www.thoughtfulhouse.org/0405-conf-glossary.htm
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| methylation |
The transfer of a methyl group to another molecule. It makes adrenaline from norepinephrine, and melatonin from serotonin. It is critical for the transcription of DNA.
Ãâó: www.thoughtfulhouse.org/0405-conf-glossary.htm
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| methylchloroisothiazolinone |
a preservative (see Methylisothiazoline)
Ãâó: www.entheos-holistic.com/glossary-terms-ingredient...
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