| lymphoma, B-cell | A group of heterogeneous lymphoid tumours generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes. (12 Dec 1998) |
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| lymphoma, diffuse | Malignant lymphoma in which neoplastic cells diffusely infiltrate the entire lymph node without any definite organised pattern. Patients whose lymphomas present a diffuse pattern generally have a more unfavorable survival outlook than those presenting with a follicular or nodular pattern. (12 Dec 1998) |
| lymphoma, follicular | Malignant lymphoma in which the lymphomatous cells are clustered into identifiable nodules within the lymph nodes. The nodules resemble to some extent the germinal centres of lymph node follicles and most likely represent neoplastic proliferation of lymph node-derived follicular centre B-lymphocytes. This class of lymphoma usually occurs in older persons, is commonly multinodal, and possibly extranodal. Patients whose lymphomas present a follicular or nodular pattern generally have a more indolent course than those presenting with a diffuse pattern. (12 Dec 1998) |
| lymphoma, high-grade | One of the three major prognostic groupings for non-hodgkin lymphomas as proposed in the working formulation of the non-hodgkin's lymphoma pathologic classification project sponsored by the national cancer institute (1981). Lymphomas falling within this group have a relatively unfavorable survival potential. (12 Dec 1998) |
| lymphoma, intermediate-grade | One of the three major prognostic groupings for non-hodgkin lymphomas as proposed in the working formulation of the non-hodgkin's lymphoma pathologic classification project sponsored by the national cancer institute (1981). Lymphomas falling within this group have an intermediate survival potential. (12 Dec 1998) |
| lymphoma, large-cell | A form of malignant lymphoma in which the malignant cells resemble histiocytes morphologically but are presently considered to be derived from lymphoid elements. These cells are irregular in shape with relatively abundant, frequently acidophilic cytoplasm. Large-cell lymphoma can occur in both nodular (follicular) and diffuse forms, with the latter being more frequently seen. (12 Dec 1998) |
| lymphoma, large-cell, diffuse | Malignant lymphoma composed of large cells which may be both cleaved and noncleaved. The pattern is predominantly diffuse. most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation. (12 Dec 1998) |
| lymphoma, large-cell, follicular | Malignant lymphoma in which the majority of neoplastic cells within the follicles are large cleaved or noncleaved cells. The degree to which the follicular centre cells retain their ability to form follicles varies with the state of B-cell transformation. (12 Dec 1998) |
| lymphoma, large-cell, immunoblastic | Malignant lymphoma characterised by the presence of immunoblasts with uniformly round-to-oval nuclei, one or more prominent nucleoli, and abundant cytoplasm. This class may be subdivided into plasmacytoid and clear-cell types based on cytoplasmic characteristics. A third category, pleomorphous, may be analogous to some of the peripheral T-cell lymphomas (lymphoma, T-cell, peripheral) recorded in both the united states and japan. (12 Dec 1998) |
| lymphoma, large-cell, ki-1 | A large-cell, non-hodgkin's, malignant lymphoma with pleomorphic appearance and reactivity with the monoclonal antibody ki-1. The lymphoma is most often found in the skin and lymph nodes and expresses the ki-1 (CD30) antigen (antigens, CD30) on its surface. It is often mistaken for metastatic carcinoma and malignant histiocytosis. (12 Dec 1998) |
| lymphoma, low-grade | One of the three major prognostic groupings for non-hodgkin lymphomas as proposed in the working formulation of the non-hodgkin's lymphoma pathologic classification project sponsored by the national cancer institute (1981). Lymphomas falling within this group have a relatively favourable survival potential. (12 Dec 1998) |
| lymphoma, lymphoblastic | A high-grade malignant lymphoma composed of a diffuse, relatively uniform proliferation of cells with round or convoluted nuclei and scanty cytoplasm. The cells are cytologically similar to the lymphoblasts seen in acute lymphocytic leukaemia, and in some cases, the disease may evolve into a leukaemic phase morphologically indistinguishable from acute t-lymphocytic leukaemia (leukaemia, T-cell, acute). Lymphoblastic lymphoma represents approximately one-third of the cases of non-hodgkin's lymphomas in children and 5% of the cases in adults. It is more prevalent in males. (12 Dec 1998) |
| lymphoma, mixed-cell | Malignant lymphoma characterised by the presence of a mixed population of cells, with the smaller cells resembling lymphocytes and the larger ones histiocytes. It usually presents in a nodular (follicular) pattern, but may evolve into a diffuse pattern. (12 Dec 1998) |
| lymphoma, mixed-cell, diffuse | A heterogeneous group of intermediate-grade lymphomas of mixed cellular composition. Although they have not been extensively studied, it appears that they are predominantly B-cell diseases. (12 Dec 1998) |
| lymphoma, mixed-cell, follicular | A low-grade malignant lymphoma of follicular pattern in which there is no clear preponderance of one cell type (small or large) over another. The large cells, cleaved or noncleaved, are often 2-3 times larger in diameter than normal lymphocytes. (12 Dec 1998) |
Synonyms : Intermediate-Grade Lymphoma, Intermediate-Grade Lymphomas, Lymphoma, Intermediate Grade, Lymphomas, Intermediate-Grade
Synonyms : Large-Cell Lymphoma, Reticulosarcoma, Histiocytic Lymphomas, Large Cell Lymphoma, Large-Cell Lymphomas, Lymphoma, Large Cell, Lymphomas, Histiocytic, Lymphomas, Large-Cell, Reticulosarcomas, Reticulum Cell Sarcoma, Reticulum-Cell Sarcomas, Sarcoma, Reticulum Cell
Synonyms : Diffuse Large Follicular Center-Cell Lymphoma, Diffuse Large-Cell Lymphoma, Large Follicular Center-Cell Lymphoma, Diffuse, Large Lymphoid Lymphoma, Diffuse, Large-Cell Lymphoma, Diffuse, Lymphoma, Diffuse Large-Cell, Lymphoma, Large Cell, Diffuse
Synonyms : Follicular Large-Cell Lymphoma, Large Lymphoid Lymphoma, Nodular, Large-Cell Lymphoma, Follicular, Lymphoma, Follicular Large-Cell, Lymphoma, Large Cell, Follicular, Lymphoma, Nodular, Large Follicular Center Cell, Follicular Large Cell Lymphoma
Synonyms : Large-Cell Immunoblastic Lymphoma, Lymphoma, Immunoblastic, Large Cell, Lymphoma, Large Cell, Immunoblastic, Diffuse Immunoblastic Lymphosarcoma, Diffuse Immunoblastic Lymphosarcomas, Immunoblastic Large Cell Lymphoma, Immunoblastic Large-Cell Lymphomas
| lymphosarcoma |
An obsolete term for a malignant tumor of lymphatic tissue.
출처: www.stjude.org/glossary
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| lymphocyte activation |
stimulation of lymphocytes by specific antigen or nonspecific mitogens resulting in macromolecular synthesis (RNA, protein, and DNA) and production of lymphokines; it is followed by proliferation and differentiation of the progeny into various effector and memory cells.
출처: www.merckmedicus.com/pp/us/hcp/thcp_dorlands_conte...
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| lymphocyte |
A general class of white blood cells that are important components of the immune system of vertebrates.
출처: www.fao.org/docrep/003/X3910E/X3910E15.htm
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| lymphoma |
Cancer originating in the lymph nodes, spleen and other lympho-reticular sites.
출처: www.fao.org/docrep/003/X3910E/X3910E15.htm
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| lymphogranuloma venereum |
a sexually transmitted chlamydial infection; common in countries with a tropical climate
출처: www.american-depot.com/services/resources_gl_l.asp
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