| myeloblastic leukaemia | A form of granulocytic leukaemia in which there are large numbers of myeloblasts in various tissues (and organs) and in the circulating blood; the immature forms may amount to 30 to 60% (or even a greater proportion) of the increased total number of white blood cells. Used synonymously for acute granulocytic leukaemia. Synonym: leukaemic myelosis. (05 Mar 2000) |
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| myelocytic leukaemia | <haematology, tumour> A form of leukaemia characterised by an uncontrolled proliferation of myelopoietic cells in the bone marrow and in extramedullary sites, and the presence of large numbers of immature and mature granulocytic forms in various tissues (and organs) and in the circulating blood. The total count may range from 1000 (aleukaemic variety) to several hundred thousand per cu mm. The predominant cell is usually of the neutrophilic series, but, in a few instances, eosinophilic or basophilic granulocytes, or even megakaryocytes, may represent the chief form; early in granulocytic leukaemia, the circulating blood may contain excessive numbers of all of the granulocytic forms. Synonym: leukaemic myelosis, myelocytic leukaemia, myelogenic leukaemia, myelogenous leukaemia, myeloid leukaemia. (05 Mar 2000) |
| polymorphocytic leukaemia | Granulocytic leukaemia, especially any variety in which the predominant cells are mature, segmented granulocytes. (05 Mar 2000) |
| myelomonocytic leukaemia | A variant of granulocytic leukaemia with monocytosis in the peripheral blood. Synonym: Naegeli type of monocytic leukaemia. (05 Mar 2000) |
| hairy cell leukaemia | <haematology, oncology> A rare chronic disorder characterised by proliferation of hairy cells in reticuloendothelial organs and blood. Origin: Gr. Haima = blood (13 Nov 1997) |
| prolymphocytic leukaemia | <haematology> A variant of chronic lymphocytic leukaemia in which the malignant cells have a more immature appearance. The disease requires chemotherapy and/or radiotherapy and sometimes removal of the spleen (splenectomy). Origin: Gr. Haima = blood (13 Nov 1997) |
| Schilling type of monocytic leukaemia | See: monocytic leukaemia. (05 Mar 2000) |
| secondary leukaemia | A leukaemia arising from either previous chemotherapy or radiotherapy or as the development of a pre-existing condition, such as myelodysplasia. Origin: Gr. Haima = blood (13 Nov 1997) |
| human leukaemia-associated antigens | Antigen's on the surface of leukaemic cells which seem not to be present on the surfaces of the same type of normal cells; the myeloblast antigen of acute myelogenous leukaemia found in chronic myelogenous leukaemia is thought to be associated with a "blastic" transformation. (05 Mar 2000) |
| human T-cell leukaemia virus | <virology> One of a group of retroviruses which causes the disease T-cell leukaemia in humans. T-cell leukaemia is a type of the cancer leukaemia where the body uncontrollably produces large amounts of abnormal (nonworking) T lymphocytes. (09 Oct 1997) |
| human T-cell lymphoma/leukaemia virus | A group of viruses (subfamily Oncovirinae, family Retroviridae) that are lymphotropic with a selective affinity for the helper/inducer cell subset of T lymphocytes and that are associated with adult T-cell leukaemia and lymphoma. Synonym: human T-cell lymphotropic virus. (05 Mar 2000) |
| smoldering leukaemia | A condition in which the bone marrow does not function normally. It does not produce enough blood cells. This condition may progress and become acute leukaemia. Smoldering leukaemia also is called myelodysplastic syndrome or preleukaemia. (12 Dec 1998) |
| splenic leukaemia | A form of leukaemia in which there is an unusually great degree of enlargement of the spleen, as observed frequently in chronic granulocytic leukaemia. (05 Mar 2000) |
| Naegeli type of monocytic leukaemia | A variant of granulocytic leukaemia with monocytosis in the peripheral blood. Synonym: Naegeli type of monocytic leukaemia. (05 Mar 2000) |
| stem cell leukaemia | A form of leukaemia in which the abnormal cells are thought to be the precursors of lymphoblasts, myeloblasts, or monoblasts. Synonym: embryonal leukaemia. (05 Mar 2000) |