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glucosone A 2-dehydrogenation (2-keto) product of glucose; a possible intermediate in the formation of glucosamine from glucose.
Origin: Glucose + -one
(05 Mar 2000)
glucosulfone sodium P,p'-Sulfonyldianiline N,N'-diglucoside disodium;a chemotherapeutic agent used in the treatment of leprosy; parenteral administration is better tolerated than oral administration.
(05 Mar 2000)
glucosulphone sodium <drug> A drug used to treat the disease leprosy. It has the chemical formula of C24H34N2Na2O18S3.
It is a yellowish white solid, a solution of which is intravenously injected into the patient.
(09 Oct 1997)
glucosuria <medicine> A condition in which glucose is discharged in the urine; diabetes mellitus.
Origin: NL, fr. E. Glucose + Gr. Urine.
Source: Websters Dictionary
(01 Mar 1998)
glucosyl The radical of glucose that has lost its hemiacetal (C-1) OH.
(05 Mar 2000)
glucosylation <biochemistry> Transfer of glucose residues, usually from the nucleotide sugar derivative UDPG.
Enzymic glucosylation to generate the glucosyl galactosyl disaccharide on the hydroxylysine of collagen is a normal process. A recent theory suggests that glucosylation of certain long lived proteins by a nonenzymic reaction with free glucose may contribute to ageing.
(18 Nov 1997)
glucosylceramidase <enzyme> A glycosidase that hydrolyzes a glucosylceramide to yield free ceramide plus glucose. Deficiency of this enzyme leads to abnormally high concentrations of glucosylceramide in the brain in gaucher's disease.
Chemical name: D-Glucosyl-N-acylsphingosine glucosylhydrolase
Registry number: EC 3.2.1.45
(12 Dec 1998)
glucosylceramide A neutral glycolipid containing equimolar amounts of fatty acid, glucose, and sphingosine (or a derivative thereof); accumulates in individuals with Gaucher disease.
Synonym: glucocerebroside.
(05 Mar 2000)
glucosylceramide beta-1-4-galactosyltransferase <enzyme> Catalyses the formation of lactosylceramide from glucosylceramide and udp galactose; also uses dihexosides as acceptor
Registry number: EC 2.4.1.-
Synonym: udpgalactose ceramide monohexoside galactosyltransferase, glccer galactosyltransferase, galt-2, udpgalactose-glucosylceramide beta-1-4-galactosyltransferase
(26 Jun 1999)
glucosylceramides Cerebrosides which contain as their polar head group a glucose moiety bound in glycosidic linkage to the hydroxyl group of ceramides. Their accumulation in tissue, due to a defect in beta-glucosidase, is the cause of gaucher's disease.
(12 Dec 1998)
glucosylglycerol-phosphate phosphatase <enzyme> Isolated from synechocystis; do not confuse with stpa protein from e. Coli
Registry number: EC 3.1.3.-
Synonym: stpa gene product, synechocystis
(26 Jun 1999)
glucosyltransferase <enzyme> An enzyme which transfers residues of glucose (a sugar) to acceptor molecules.
(09 Oct 1997)
glucosyltransferases <enzyme> Enzymes that catalyze the transfer of glucose from a nucleoside diphosphate glucose to an acceptor molecule which is frequently another carbohydrate.
Registry number: EC 2.4.1.-
(12 Dec 1998)
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