| Langhans giant cell | Multinucleate cells formed by fusion of epithelioid macrophages and associated with the central part of early tubercular lesions. Similar to foreign body giant cells, but with the nuclei peripherally located. (18 Nov 1997) |
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| Langhans'-type giant cells | Multinucleated giant cell's seen in tuberculosis and other granulomas; the nuclei are arranged in an arciform manner at the periphery of the cell's. Synonym: Langhans'-type giant cells. Synonym: cytotrophoblastic cells. (05 Mar 2000) |
| foreign body giant cell | <pathology> Syncytium formed by the fusion of macrophages in response to an indigestible particle too large to be phagocytosed for example talc, silica or asbestos fibres). There may be as many as 100 nuclei randomly distributed: similar cells but with the nuclei more peripherally located (Langhans cells) are found at the centre of tuberculous lesions. (06 Mar 1998) |