| CAM | calf aortic microsome; cell adhesion molecule; cell-associating molecule; chorioallantoic membrane; ... |
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| CCL | carcinoma cell line; certified cell line; Charcot-Leyden crystal; continuing care level; critical ca... |
| CDC | calculated date of confinement; cancer diagnosis center; capillary diffusion capacity; cell division... |
| CI | cardiac index; cardiac insufficiency; cell immunity; cell inhibition; cephalic index; cerebral infar... |
| CMI | carbohydrate metabolism index; care management integration; case mix index; cell-mediated immunity; ... |
| haemorrhagic anaemia | Anaemia resulting directly from loss of blood. (05 Mar 2000) |
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| primary erythroblastic anaemia | The dire disease also known as beta thalassaemia. The clinical picture of this form of anaemia was first described in 1925 by the paediatrician thomas benton cooley. Other names for the disease are cooley's anaemia and mediterranean anaemia. The term thalassaemia was coined by the nobel prise winning pathologist george whipple and the professor of paediatrics william bradford at u. Of rochester because thalassa in greek means the sea (like the mediterrranean sea) + -aemia means in the blood so thalassaemia means sea in the blood. Thalassaemia is not just one disease. It is a complex contingent of genetic (inherited) disorders all of which involve underproduction of haemoglobin, the indispensable molecule in red blood cells that carries oxygen. The globin part of normal adult haemoglobin is made up of 2 alpha and 2 beta polypeptide chains. In beta thalassaemia, there is a mutation (change) in both beta globin chains leading to underproduction (or absence) of beta chains, underproduction of haemoglobin, and profound anaemia. The gene for beta thalassaemia is relatively frequent in people of mediterranean origin (for example, from italy and greece). Children with this disease inherit one gene for it from each parent (and so are said to be homozygous for beta thalassaemia). The parents are carriers (heterozygotes) with just one thalassaemia gene, are said to have thalassaemia minor, and are essentially normal. Their children affected with beta thalassaemia seem entirely normal at birth (because at birth we still have predominantly foetal haemoglobin which does not contain beta chains) but the anaemia emerges in the first few months of life and becomes progressively more severe leading to pallor and easy fatiguability, failure to thrive (grow), bouts of fever (due to infections) and diarrhoea. Treatment based on blood transfusions is helpful but not curative. Gene therapy will, it is hoped, be applicable to this disease. (12 Dec 1998) |
| primary refractory anaemia | Any of a group of anaemic conditions in which there is persistent, frequently advanced anaemia that is not successfully treated by any means except blood transfusions, and that is not associated with another primary disease. (05 Mar 2000) |
| Heinz body anaemia | A congenital haemolytic anaemia, due to autosomal inheritance of one of many unstable haemoglobins. The anaemia is of variable severity and characterised by the presence in vivo or in vitro of Heinz bodies. (05 Mar 2000) |
| hemolytic anaemia | <disease, haematology> Anaemia resulting from reduced red cell survival time and haemolysis, either due to an intrinsic defect in the erythrocyte (hereditary spherocytosis or ellipsocytosis, enzyme defects, haemoglobinopathy) or an extrinsic damaging agent. For example autoantibody (autoimmune haemolytic anaemia), iso antibody, parasitic invasion of the cells (malaria), bacterial or chemical haemolysins, mechanical damage to erythrocytes. Origin: Gr. Haima = blood (18 Nov 1997) |
| scorbutic anaemia | Anaemia occurring in patients with scurvy, usually due to coincident nutritional deficiency; e.g., the "megaloblastic anaemia of scurvy" is due to concomitant folic acid deficiency. (05 Mar 2000) |
| secondary refractory anaemia | Any persistent anaemia that is successfully treated only by blood transfusions, and that is associated with another condition. (05 Mar 2000) |
| hookworm anaemia | Anaemia associated with heavy infestation by Ancylostoma duodenale or Necator americanus. (05 Mar 2000) |
| sideroblastic anaemia | <haematology> A form of refractory anaemia caused by sideroblasts in the bone marrow. Origin: Gr. Haima = blood (09 Oct 1997) |
| hyperchromic anaemia | <haematology> A type of anaemia which results when the body lacks sufficient vitamin B and the resulting red blood cells are thicker than normal, appearing more deeply coloured. Origin: Gr. Haima = blood (11 Jan 1998) |
| hypochromic anaemia | Anaemia characterised by a decrease in the ratio of the weight of haemoglobin to the volume of the erythrocyte, i.e., the mean corpuscular haemoglobin concentration is less than normal; the individual cells contain less haemoglobin than they could have under optimal conditions. (05 Mar 2000) |
| hypochromic microcytic anaemia | Anaemia due to iron deficiency or thalassaemia, and characterised by lower than normal mean corpuscular volume, mean corpuscular haemoglobin, and mean corpuscular haemoglobin concentration. (05 Mar 2000) |
| hypoferric anaemia | Hypochromic microcytic anaemia characterised by low serum iron, increased serum iron-binding capacity, decreased serum ferritin, and decreased marrow iron stores. Synonym: hypoferric anaemia. (05 Mar 2000) |
| hypoplastic anaemia | <haematology> A low red blood cell count that results from the underproduction of red blood cells by the bone marrow. This is often secondary to a drug (chemotherapy) side effect. (27 Sep 1997) |
| hypoproliferative anaemia | <haematology> Anaemia which results from abnormally low levels of red blood cells and haemoglobin in the blood. It is caused because the person has too few of the stem cells which make the red blood cells. (09 Oct 1997) |