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MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 7
  • Complement C5a - »õâ The minor fragment formed when C5 convertase cleaves C5 into C5a and COMPLEMENT C5B. C5a is a 74-amino-acid glycopeptide with a carboxy-terminal ARGININE that is crucial for its spasmogenic activity. Of all the complement-derived anaphylatoxins, C5a is the most potent in mediating immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE), smooth MUSCLE CONTRACTION; HISTAMINE RELEASE; and migration of LEUKOCYTES to site of INFLAMMATION.
    Synonyms : C5a Complement, Complement 5a, Complement Component 5a, 5a, Complement Component, C5a, Complement, Complement, C5a, Component 5a, Complement
  • Complement C5a, des-Arginine - »õâ A derivative of complement C5a, generated when the carboxy-terminal ARGININE is removed by CARBOXYPEPTIDASE B present in normal human serum. C5a des-Arg shows complete loss of spasmogenic activity though it retains some chemotactic ability (CHEMOATTRACTANTS).
    Synonyms : C5 a, des-Arg, C5 a, des-Arginine, C5a des-Arg, C5a des-Arginine, C5a, des-Arg, C5a, des-Arginine, Complement 5a, de-Arginine, Complement 5a, des-Arginine, C5 a, des Arg, C5 a, des Arginine, C5a des Arginine, C5a, des Arg, C5a, des Arginine, des-Arg C5 a
  • Complement C5b - »õâ The larger fragment generated from the cleavage of C5 by C5 CONVERTASE that yields COMPLEMENT C5A and C5b (beta chain + alpha' chain, the residual alpha chain, bound by disulfide bond). C5b remains bound to the membrane and initiates the spontaneous assembly of the late complement components to form C5b-8-poly-C9, the MEMBRANE ATTACK COMPLEX.
    Synonyms : C5b Complement, Complement 5b, Complement Component 5b, C5b, Complement, Complement, C5b, Component 5b, Complement
  • Complement C6 - »õâ A 105-kDa serum glycoprotein with significant homology to the other late complement components, C7-C9. It is a polypeptide chain cross-linked by 32 disulfide bonds. C6 is the next complement component to bind to the membrane-bound COMPLEMENT C5B in the assembly of MEMBRANE ATTACK COMPLEX. It is encoded by gene C6.
    Synonyms : C6 Complement, Complement 6, Complement Component 6, C6, Complement, Complement, C6, Component 6, Complement
  • Complement C7 - »õâ A 93-kDa serum glycoprotein encoded by C7 gene. It is a polypeptide chain with 28 disulfide bridges. In the formation of MEMBRANE ATTACK COMPLEX; C7 is the next component to bind the C5b-6 complex forming a trimolecular complex C5b-7 which is lipophilic, resembles an integral membrane protein, and serves as an anchor for the late complement components, C8 and C9.
    Synonyms : C7 Complement, Complement 7, Complement Component 7, C7, Complement, Complement, C7, Component 7, Complement
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MeSH(Medical Subject Headings) À¯»ç °Ë»ö (http://www.nlm.nih.gov) °á°ú : 0 ÆäÀÌÁö: 7
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