| cylindromatous carcinoma | <tumour> A histologic type of carcinoma characterised by large epithelial masses containing round, glandlike spaces or cysts which frequently contain mucus or collagen and are bordered by a few or many layers of epithelial cells without intervening stroma, forming a cribriform pattern like a slice of Swiss cheese; perineural invasion and haematogenous metastasis are common; occurs most commonly in salivary glands. Synonym: cylindromatous carcinoma. (05 Mar 2000) |
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| cystic carcinoma | <tumour> A carcinoma in which true epithelium-lined cysts are formed, or degenerative changes may result in cystlike spaces. (05 Mar 2000) |
| primary carcinoma | <tumour> Carcinoma at the site of origin, with local invasion in that organ. (05 Mar 2000) |
| primary neuroendocrine carcinoma of the skin | A rare malignant cutaneous tumour seen in sun-exposed skin of elderly patients composed of dermal nodules of small round cells with scanty cytoplasm in a trabecular pattern; the tumour cells contain cytoplasmic dense core granules resembling neurosecretory granules seen in Merkel cells. Synonym: primary neuroendocrine carcinoma of the skin, trabecular carcinoma. (05 Mar 2000) |
| sarcomatoid carcinoma | <tumour> A carcinoma composed of elongated cells, frequently a poorly differentiated squamous cell carcinoma which may be difficult to distinguish from a sarcoma. Synonym: sarcomatoid carcinoma. (05 Mar 2000) |
| hepatocellular carcinoma | <oncology, tumour> A tumour of the liver. The most common primary malignant liver tumour is hepatocellular carcinoma. Risk factors include chronic active hepatitis B and cirrhosis of the liver (for example alcohol aetiology). (27 Sep 1997) |
| prostate carcinoma | <radiology> Treatment: stages A and B: radical prostatectomy (prostate, seminal vesicles, part of bladder); some do simple prostatectomy for stage A, stage C: radiation therapy, stage D: orchiectomy and/or oestrogens stage A Tumour discovered incidentally in tissue removed for BPH, A1 Small focal involvement of one lobe, A2 Multifocal or diffuse carcinoma, Stage B Palpable carcinoma confined to prostate on digital exam, B1 Solitary nodule less than 1.5 cm, B2 Diffuse involvement of both lobes, Stage C Tumour extending through the prostate capsule; no metastasis, Stage D Metastases, usually to bone and/or pelvic lymph nodes (12 Dec 1998) |
| scar carcinoma | <tumour> Carcinoma of the lung, usually adenocarcinoma, arising from a peripheral lung scar or associated with interstitial fibrosis in a honeycomb lung. Synonym: scar cancer. (05 Mar 2000) |
| scirrhous carcinoma | <tumour> A hard carcinoma, fibrous in nature, resulting from a desmoplastic reaction by the stromal tissue to the presence of the neoplastic epithelium. Synonym: fibrocarcinoma. (05 Mar 2000) |
| secondary carcinoma | <tumour> A carcinoma that has appeared in a region remote from its site of origin, as in metastasis. Synonym: secondary carcinoma. (05 Mar 2000) |
| secretory carcinoma | <tumour> Carcinoma of the breast with pale-staining cells showing prominent secretory activity, as seen in pregnancy and lactation, but found mostly in children. Synonym: juvenile carcinoma. (05 Mar 2000) |
| Hurthle cell carcinoma | A neoplasm of the thyroid gland composed of polyhedral acidophilic cells, thought by some to be oncocytes; it may be benign or malignant, the behaviour of the latter depending on the general microscopic pattern, whether follicular, papillary, or undifferentiated. See: Hurthle cell adenoma. Synonym: Hurthle cell carcinoma. (05 Mar 2000) |
| signet-ring cell carcinoma | <tumour> A poorly differentiated adenocarcinoma composed of cells with a cytoplasmic droplet of mucus that compresses the nucleus to one side along the cell membrane; arises most frequently in the stomach, occasionally in the large bowel or elsewhere. (05 Mar 2000) |
| small cell carcinoma | <oncology, tumour> Common malignant neoplasm of bronchus. Cells of the tumour have endocrine like characteristics and may secrete one or more of a wide range of hormones, especially regulatory peptides like bombesin. (18 Nov 1997) |
| spindle cell carcinoma | <tumour> A carcinoma composed of elongated cells, frequently a poorly differentiated squamous cell carcinoma which may be difficult to distinguish from a sarcoma. Synonym: sarcomatoid carcinoma. (05 Mar 2000) |