| 17-hydroxylase deficiency syndrome | <syndrome> Congenital deficiency of adrenocortical, and possibly ovarian, steroid C-17a hydroxylase; the resulting excessive secretion of corticosterone and deoxycorticosterone produces hypertension and hypokalaemic alkalosis; absence of aldosterone secretion in such patients may indicate a multiple enzymic deficiency. (05 Mar 2000) |
|---|---|
| 2,4-dichlorophenol hydroxylase | <enzyme> Nadph-dependent; forms 3,5-dichlorocatechol Registry number: EC 1.14.13.- Synonym: 2,4-dichlorophenol 6-monooxygenase (26 Jun 1999) |
| 25-hydroxycholecalciferol 1-hydroxylase | <enzyme> An enzyme that catalyses the formation of 1,25-dihydroxycholecalciferol from 25-hydroxycholecalciferol. The reaction requires oxygen, magnesium, and NAD(p)h. Chemical name: Calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating) Registry number: EC 1.14.13.13 (12 Dec 1998) |
| 25-hydroxycholecalciferol-24-hydroxylase | <enzyme> Cytochrome p-450 monooxygenase system Registry number: EC 1.14.99.- Synonym: 25-hydroxyvitamin d(3)-24-hydroxylase, 25-hydroxyvitamin d(3)-24r-hydroxylase, 25-hc-24-hydroxylase, cytochrome p450cc24, 24-hydroxylase cytochrome p-450, cytochrome p450(24), vitamin d 24-hydroxylase, cyp24 (26 Jun 1999) |
| 25-hydroxycholesterol 7alpha-hydroxylase | <enzyme> Catalyses 7alpha hydroxylation of 25-hydroxycholesterol in liver microsomes; from rat, pig and human; different from cholesterol 7alpha hydroxylase Registry number: EC 1.14.99.- Synonym: 25-hc 7alpha-hydroxylase (26 Jun 1999) |
| 2-hydroxy-isonicotinic acid hydroxylase | <enzyme> Forms 2,6-dihydroxy-isonicotinic acid (citrazinic acid); contains iron and a flavin; incorporates hydroxyl group of water Registry number: EC 1.- Synonym: hinah (26 Jun 1999) |
| 3-(3-hydroxyphenyl)propionate hydroxylase | <enzyme> Isolated from rhodococcus globerulus; has been sequenced; genbank u89712 Registry number: EC 1.14.- Synonym: 3hpp hydroxylase, hppa gene product (hydroxylase) (26 Jun 1999) |
| 3,9-dihydroxypterocarpan-6a-hydroxylase | <enzyme> Requires NADPH; stereospecific microsomal monooxygenase from elicitor-challenged soybean cell cultures; involved in glyceollin biosynthesis Registry number: EC 1.14.13.- Synonym: 3,9-dhpc-6-hydroxylase (26 Jun 1999) |
| 3-hydroxybenzoate-6-hydroxylase | <enzyme> From micrococcus; a flavoprotein; catalyses reversibly the hydroxylation of 3-hydroxybenzoate in the presence of NADH and o2 to form 2,5-dihydroxybenzoate, nad and h2o Registry number: EC 1.14.13.24 Synonym: 3-hydroxybenzoate-6-monooxygenase, 3-ohb-6-hydroxylase, 3-hydroxybenzoate 6-hydroxylase (26 Jun 1999) |
| 3-hydroxyphenylacetate 6-hydroxylase | <chemical> Fad-dependent monooxygenase from a flavobacterium species; requires nadhor NADPH; forms 2,5-dihydroxyphenylacetate (26 Jun 1999) |
| 4-aminobenzoate hydroxylase | <enzyme> Catalyses decarboxylative hydroxylation of 4-aminobenzoate forming 4-hydroxyaniline in presence of NADPH and o2; fad-dependent monooxygenase from agaricus bisporus Registry number: EC 1.14.13.27 (26 Jun 1999) |
| 4-androstene-3,17-dione-16 beta-hydroxylase | <enzyme> Catalyses androst-4-en-3,17-dione to 16 beta-hydroxyandrost-4-en-3,17-dione; cytochrome p450 2b1 is both a androstenedione 16beta-hydroxylase and a testosterone 16beta-hydroxylase Registry number: EC 1.14.99.- Synonym: aedo-16-hydroxylase, steroid 16-hydroxylase, cytochrome p450 2b2, cyp 2b2, cyp2b2 (26 Jun 1999) |
| 4-coumaroyl-coenzyme A 3-hydroxylase | <enzyme> Catalyses the formation of trans-caffeoyl-CoA from trans-4-coumaroyl-CoA; requires ascorbic acid and zinc Registry number: EC 1.14.17.- Synonym: 4-coumaroyl-CoA 3-hydroxylase (26 Jun 1999) |
| 4-coumaroyl-D-glucose hydroxylase | <enzyme> From sweet potato roots (ipomoea batatas); catalyses the conversion of p-coumaroyl-d-glucose to caffeoyl-d-glucose for chlorogenic acid biosynthesis in the presence of ascorbic acid; mw 33 kD; has weak polyphenol oxidase activity; also hydroxylates p-coumaric acid Registry number: EC 1.14.17.- Synonym: p-coumaroyl-d-glucose hydroxylase, cdg hydroxylase (26 Jun 1999) |
| 4-hydroxy-5-polyprenylbenzoate hydroxylase | <enzyme> Involved in ubiquinone biosynthesis Registry number: EC 1.14.13.- Synonym: 4-oh-5-ppb hydroxylase (26 Jun 1999) |