| alpha-(4-O-methyl)-D-glucuronidase | <enzyme> Removes 4-o-methyl-glucopyranosyl uronic acid residues from the 2-position of fungal cell wall xylans Registry number: EC 3.2.1.- Synonym: 4-o-methyl-glucuronidase (26 Jun 1999) |
|---|---|
| alpha-actinin | An F-actin binding protein in vertebrate cells that cross-links actin filaments into regular parallel arrays. (05 Mar 2000) |
| alpha-adrenergic blocking agent | An agent that competitively blocks alpha-adrenergic receptors; used in the treatment of hypertension. Synonym: alpha-blocker. (05 Mar 2000) |
| alpha-adrenergic receptors | Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as phenoxybenzamine, to block only some adrenergic receptor's and of other agents, such as methoxamine, to activate only the same adrenergic receptor's. Such receptor's are designated as alpha-receptors. Their activation results in physiological responses such as increased peripheral vascular resistance, mydriasis, and contraction of pilomotor muscles. (05 Mar 2000) |
| alpha alcoholism | Jellinek's term for a still controllable and strictly psychological dependence on alcohol, as to relieve emotional or physical pain, with resulting interference with interpersonal relationships. (05 Mar 2000) |
| alpha-allocortol | 5alpha-Pregnane-3a,11b,17,20a,21-pentaol;the 5a enantiomer of alpha-cortol; a metabolite of hydroxycortisone found in the urine. (05 Mar 2000) |
| alpha-allocortolone | 3a,17,20a,21-Tetrahydroxy-5alpha-pregnane-11-one;the 5a enantiomer of alpha-cortolone; a metabolite of hydrocortisone found in urine. (05 Mar 2000) |
| alpha-allopregnanediol | 5alpha-Pregnane-3a,20alpha-diol;a metabolite of progesterone and adrenocortical hormones, found in urine. (05 Mar 2000) |
| alpha-amanitin | <drug> A highly toxic, heat-stable bicyclic oligopeptide derived from the Amanita phalloides mushroom. It inhibits transcription by interfering with the function of certain RNA polymerases. (14 Aug 2000) |
| alpha-aminoacyl-peptide hydrolases | <enzyme> Registry number: EC 3.4.11. (12 Dec 1998) |
| alpha-aminoadipyl-cysteinyl-valine synthetase | <enzyme> As of 9/27/95 this has been separated from isopenicillin n synthetase Registry number: EC 6.3.2.- Synonym: acv synthetase, aa-cysteine synthetase, delta-(alpha-aminoadipyl)-cys-val synthetase, delta-(l-alpha-aminoadipyl)-l-cyteinyl-d-valine synthetase, pcbab gene product, acva gene product (26 Jun 1999) |
| alpha-amylase | <enzyme> An enzyme that catalyses the endohydrolysis of 1,4-alpha-glycosidic linkages in starch, glycogen, and related polysaccharides and oligosaccharides containing 3 or more 1,4-alpha-linked d-glucose units. Pharmacological action: anti-inflammatory agents. Chemical name: 1,4-alpha-D-Glucan glucanohydrolase Registry number: EC 3.2.1.1 (12 Dec 1998) |
| alpha angle | The angle between the visual and optic axes as they cross at the nodal point of the eye, the angle between the visual line and the major axis of the corneal ellipse. (05 Mar 2000) |
| alpha-antitrypsin deficiency | <enzyme> A specific enzyme (alpha 1 antitrypsinase) that when absent genetically can result in panacinar emphysema (lung disease) and liver disease. There is no specific treatment for this condition other than supportive care for the liver and lung complications. Medications such as alpha-1proteinase inhibitor is given regularly to these patients. Incidence: approximately 1 in 10,000. (02 Jan 1998) |
| alpha,beta-ketoalkene reductase | <enzyme> Nadh is much less effective than NADPH; catalyses the reduction of the carbon-carbon double bond of five membered ring cpds which have two conjugated carbonyl groups on both sides of a double bond Registry number: EC 1.3.1.- Synonym: n-ethylmaleimide reducing enzyme, NADPH-linked alpha,beta-ketoalkene double bond reductase, n-ethylmaleimide reductase (26 Jun 1999) |