| DAP | data acquisition processor; depolarizing afterpotential; diabetes-associated peptide; diaminopimelic... |
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| DSIP | delta sleep-inducing peptide |
| FPB | femoral popliteal bypass; fibrino-peptide B; flexor pollicis brevis |
| GIP | gastric inhibitory polypeptide; giant cell interstitial pneumonia; glucose-dependent insulinotropic ... |
| GLP | glucagon-like peptide; glucose-L-phosphate; glycolipoprotein; good laboratory practice; group living... |
| C chain | <protein> C-peptide is a byproduct of normal insulin production by the beta cells in the pancreas. Normal values are 0.5 to 3.0 ng/ml. Normal levels indicate that the body is still producing its own insulin. Low levels indicate that the pancreas is producing little or no insulin. Elevations can be seen in cases of insulinomas and islet of Langerhans tumours. (27 Sep 1997) |
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| medium-chain acyl-CoA dehydrogenase | <enzyme> Deficiency in mitochondrial beta oxidation of fatty acids gives a disorder frequently masquerading as reye syndrome or sudden infant death; leads to buildup of octanoyl carnitine in urine Registry number: EC 1.3.- Synonym: mcaca-dehydrogenase, medium-chain acyl-coenzyme a dehydrogenase, octanoyl-CoA dehydrogenase, mcad enzyme (26 Jun 1999) |
| respiratory chain | The mitochondrial electron transport chain. (18 Nov 1997) |
| glycyl chain | A polypeptide component of insulin containing 21 amino acyl residues, beginning with a glycyl residue (NH2-terminus); insulin is formed by the linkage of an A chain to a B chain by two disulfide bonds; the amino-acid composition of the A chain is a function of species. Synonym: glycyl chain. In general, one of the polypeptides in a multiprotein complex. (05 Mar 2000) |
| chain | 1. In chemistry, a series of atoms held together by one or more covalent bonds. 2. In bacteriology, a linear arrangement of living cells that have divided in one plane and remain attached to each other. Origin: L. Catena (05 Mar 2000) |
| chain-compensated spirometer | A Tissot spirometer in which compensation for change in bell buoyancy is accomplished automatically by a suspending chain of correct mass per unit length. (05 Mar 2000) |
| chain isomer | <chemistry> One of two or more compounds having the same chemical composition but differing in the arrangement of the atoms (usually carbon atoms) forming the backbone of the structure of the compounds. (21 Mar 1998) |
| chain reaction | A reaction in which a product reacts and thus continues the reaction. (09 Oct 1997) |
| chain reflex | A series of reflexs, each serving as a stimulus for the next. (05 Mar 2000) |
| phenylalanyl chain | A polypeptide component of insulin containing 30 amino acyl residues, beginning with a phenylalanyl residue (NH2-terminus); insulin is formed by the linkage of a B chain to an A chain by two disulfide bonds; the amino-acid composition of the B chain is a function of species. Synonym: phenylalanyl chain. (05 Mar 2000) |
| closed chain compound | Any compound in which the constituent atoms, or any part of them, form a ring. Used mainly in organic chemistry where: 1) numerous compound's contain rings of carbon atoms (carbocyclic compound's) or carbon atoms plus one or more atoms of other types (heterocyclic compound's), usually nitrogen, oxygen, or sulfur; 2) where the atoms in the ring are all of the same element (homocyclic or isocyclic compound); 3) where the ring is saturated or contains nonconjugated double bonds (alicyclic compound), the compound is similar in properties to the corresponding acyclic compound (e.g., cyclohexane resembles hexane); 4) where the ring contains conjugated double bonds in a closed loop in which there are 4n + 2 (where n is an integer) delocalised π electrons (Huckel's rule) (aromatic compound; e.g., benzene, pyridine), it is more stable than the corresponding saturated ring and exhibits unusual chemical properties characteristic of itself and not of other types of rings or of acyclic compound's. These aromatic compounds have the ability to sustain an induced ring current. Synonym: closed chain compound, ring compound. (05 Mar 2000) |
| cold chain | A system of protection against high environmental temperatures for heat-labile vaccines, sera and other biological preparations. (05 Mar 2000) |
| P light chain | <protein> Myosin light chain that can be phosphorylated by myosin light chain kinase, as a result of phosphorylation, the myosin is activated. (18 Nov 1997) |
| corticosteroid side-chain-isomerase | <enzyme> Converts 11-deoxycorticosterone to 20-hydroxy-3-oxypregn-4-en-21-al; also acts as an epimerase at c-20 Registry number: EC 5.3.1.21 Synonym: corticosteroid side chain isomerase, ccsci (26 Jun 1999) |
| polymerase chain reaction | <molecular biology, technique> The first practical system for in vitro amplification of DNA and as such one of the most important recent developments in molecular biology. Two synthetic oligonucleotide primers, which are complementary to two regions of the target DNA (one for each strand) to be amplified, are added to the target DNA (that need not be pure), in the presence of excess deoxynucleotides and Taq polymerase, a heat stable DNA polymerase. In a series (typically 30) of temperature cycles, the target DNA is repeatedly denatured (around 90_C), annealed to the primers (typically at 50-60_C) and a daughter strand extended from the primers (72_C). As the daughter strands themselves act as templates for subsequent cycles, DNA fragments matching both primers are amplified exponentially, rather than linearly. The original DNA need thus be neither pure nor abundant and the polymerase chain reaction has accordingly become widely used not only in research, but in clinical diagnostics and forensic science. Acronym: PCR (14 Oct 1997) |
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