| phenothiazine | <pharmacology> A group of tranquilising medications with antipsychotic action, thought to act by blocking dopaminergic transmission in the brain. They are used to treat mental, nervous and emotional disorders. Examples include: chlorpromazine, fluphenazine, mesoridazine, perphenazine, prochlorperazine, promazine, thioridazine, trifluoperazine, thiopropazate and triflupromazine. Trifluoperazine binds to and inhibits calmodulin and has been used experimentally to block calcium or calmodulin controlled reactions. (29 Sep 1997) |
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| phenothiazine sulfoxidase | <enzyme> Converts ethionamide, chlorpromazine and thioridazine to their corresponding sulfoxides; requires NADPH and oxygen; does not contain p-450 Registry number: EC 1.8.- Synonym: ethionamide sulfoxidase (26 Jun 1999) |
| phenotype | <biology, genetics> The total characteristics displayed by an organism under a particular set of environmental factors, regardless of the actual genotype of the organism. Results from interaction between the genotype and the environment. (09 Jan 1998) |
| phenotypic | Relating to phenotype. (05 Mar 2000) |
| phenotypic threshold | A quantitative genetic trait with a continuous distribution termed its liability may generate two kinds of phenotype, according to whether the liability lies above or below some critical threshold at about which a radical change in behaviour occurs. For instance, blood uric acid level is a liability with an approximately gaussian distribution. At a critical point of chemical saturation (the threshold crystallization occurs and the resulting gout or nongout is a threshold trait. (05 Mar 2000) |
| phenotypic value | In quantitative genetics, the metrical quantity of some trait associated with a particular phenotype. (05 Mar 2000) |
| phenoxazine | Phenothiazine in which S is replaced by O; as the 3-oxo derivative (phenoxazone), phenoxazine is the chromophore of actinomycins. (05 Mar 2000) |
| phenoxazone | See: phenoxazine. (05 Mar 2000) |
| phenoxybenzamine | <chemical> N-(2-chloroethyl)-n-(1-methyl-2-phenoxyethyl) benzenemethanamine. An alpha-adrenergic anatagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator. Pharmacological action: adrenergic alpha-antagonists, antihypertensive agents, sympatholytics, vasodilator agents. Chemical name: Benzenemethanamine, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)- (12 Dec 1998) |
| phenoxybenzamine hydrochloride | (2-Chloroethyl)-N-(1-methyl-2-phenoxyethyl benzylamine hydrochloride;a potent adrenergic (alpha-receptor) blocking agent of the beta-haloalkylamines; selectively blocks the excitatory response of smooth muscle and exocrine glands to epinephrine; used in the treatment of peripheral vascular diseases and in pheochromocytoma. (05 Mar 2000) |
| phenoxybenzoate dioxygenase | <enzyme> Catalyses conversion of 3- or 4-phenoxybenzoate to phenol and protocatechuate via a putative hemiacetal intermediate. Registry number: EC 1.14.14.- Synonym: 4-carboxydiphenyl ether dioxygenase, pob dioxygenase, pobb gene product (26 Jun 1999) |
| phenoxymethylpenicillin | <chemical> (2s-(2 alpha,5 alpha,6 beta)-3,3-dimethyl-7-oxo-6-((phenoxyacetyl)amino)-4-thia-1- azabicyclo(3.2.0)heptane-2-carboxylic acid. A broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms. Pharmacological action: penicillins. Chemical name: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenoxyacetyl)amino)-, (2S-(2alpha,5alpha,6beta))- (12 Dec 1998) |
| phenoxymethylpenicillin amidohydrolase | <enzyme> Isolated from penicillium chrysogenes; hydrolyses phenoxymethylpenicillin to 6-aminopenicillanic acid (6-apa) Registry number: EC 3.5.1.- Synonym: pmp amidase (26 Jun 1999) |
| phenozygous | Having a narrow cranium as compared with the width of the face, so that when the skull is viewed from above, the zygomatic arches are visible. Origin: G. Phaino, to show, + zygon, yoke (05 Mar 2000) |
| phenpentermine tartrate | A,a,beta-Trimethylphenethylamine;an anorexigenic agent. (05 Mar 2000) |
Synonyms : Falithrom, Hexal Brand of Phenprocoumon, Liquamar, Marcoumar, Marcumar, Phenprogramma, Roche Brand of Phenprocoumon, Worwag Brand of Phenprocoumon
Synonyms : Adipex-P, Duromine, Ionamine, Phentermine Hydrochloride, Adipex P, AdipexP, Hydrochloride, Phentermine
Synonyms : Alliance Brand of Phentolamine Mesylate, Novartis Brand of Phentolamine Mesylate, Paladin Brand of Phentolamine Mesylate, Phentolamine Mesilate, Phentolamine Mesylate, Phentolamine Methanesulfonate, Phentolamine Mono-hydrochloride, Regitine, Regityn, Rogitine
Synonyms : Ethers, Phenyl, Oxides, Diphenyl
Synonyms :
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| phenol motor point block |
the most common method of motor point block; a solution of 5 per cent phenol in water is injected at the motor point. Called also phenol b.
Ãâó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
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| phenotypic adaptation |
a change in the structural and physiological properties of an organism in response to a genetic mutation or to a change in environment.
Ãâó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
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| phenol coefficient |
a measure of the bactericidal activity of a chemical compound in relation to phenol. The test is standardized (Rideal-Walker method, US Department of Agriculture method). The coefficient is calculated by dividing the concentration of the test compound at which it kills the test organism in 10 minutes, but not in 5 minutes, by the concentration of phenol that kills the organism under the same conditions. ...
Ãâó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
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| pheochromocytoma |
A pheochromocytoma (also phaeochromocytoma, English spelling) is a tumor in the medulla of the adrenal glands (or, rarely, the ganglia of the sympathetic nervous system) which secretes excessive amounts of catecholamines, usually epinephrine and norepinephrine. The signs and symptoms of a pheochromocytoma are those of sympathetic nervous system hyperactivity: elevated heart rate and blood pressure and anxiety often resembling that of a panic attack. ...
Ãâó: en.wikipedia.org/wiki/Pheochromocytoma
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| pheresis |
Pheresis (pronounced as fur-ee-sis) is a special kind of blood donation by which specific components of the blood can be separated. It came from a Greek word meaning 'to take away' or 'separate'. By this method, the blood components like plasma, erythrocytes, platelets, granulocytes (neutrophils and basophils), and agranulocytes (lymphocytes and monocytes) can be separated. The pheresis is done using a machine called a cell separator. ...
Ãâó: en.wikipedia.org/wiki/Pheresis
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