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Paget's d. 1. intraductal carcinoma of the breast extending to involve the nipple and areola, characterized clinically by eczema-like inflammatory skin changes, and histologically by infiltration of the epidermis by malignant cells (Paget's cells).  2. a neoplasm of the vulva and sometimes the perianal region histologically and clinically quite similar to Paget's disease of the breast, but having less of a tendency to be associated with underlying invasive carcinoma. Called also extramammary or vulvar Paget's d.  3. osteitis deformans.
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Paget's d. of bone osteitis deformans.
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Paget's d., extramammary Paget's d. (def. 2).
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Paget's d., vulvar Paget's d. (def. 2).
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Paget's quiet n. a process of local necrosis and sequestrum formation in the superficial layers of the shaft of a long bone with a minimal amount of suppuration around the sequestrum and without sinus formation.
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