| proto-oncogene proteins c-mos | Cellular proteins encoded by the c-mos genes (genes, mos). They function in the cell cycle to maintain maturation-promoting factor in the active state and have protein-serine/threonine kinase activity. Oncogenic transformation can take place when c-mos proteins are expressed at the wrong time. (12 Dec 1998) |
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| proto-oncogene proteins c-myc | Cellular DNA-binding proteins encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumourigenesis. (12 Dec 1998) |
| proto-oncogene proteins c-raf | <enzyme> A class of serine-threonine kinases involved in cellular signal transduction. Included in this class are the proto-oncogene proteins mil and raf. Raf is a component of a signal transduction pathway leading to increased gene expression through the c-jun DNA binding site, ap1. Registry number: EC 2.7.10.- (12 Dec 1998) |
| protozoan proteins | Proteins found in any species of protozoan. (12 Dec 1998) |
| prpc proteins | Normal cellular isoform of prion proteins (prions) encoded by a chromosomal gene and found in normal and scrapie-infected brain tissue, and other normal tissue. Prpc are protease-sensitive proteins whose function is unknown. Posttranslational modification of prpc into prpsc leads to infectivity. (12 Dec 1998) |
| prpsc proteins | Abnormal isoform of prion proteins (prions) resulting from a posttranslational modification of the cellular prion protein (prpc proteins). Prpsc are disease-specific proteins seen in certain human and animal neurodegenerative diseases (prion diseases). (12 Dec 1998) |
| high mobility group proteins | Family of small, nonhistone, nuclear proteins. Some appear to be involved in controlling transcription. (18 Nov 1997) |
| homeodomain proteins | Proteins encoded by homeobox genes (genes, homeobox) that exhibit structural similarity to certain prokaryotic and eukaryotic DNA-binding proteins. Homeodomain proteins are involved in the control of gene expression during morphogenesis and development (gene expression regulation, developmental). (12 Dec 1998) |
| homologous proteins | <molecular biology> Proteins that look similar and work in similar ways in different species. (09 Oct 1997) |
| serum proteins | Dissolved protein's (more than 100) of blood plasma, mainly albumins and globulins (normally 6 to 8 g/100 ml); they hold fluid in blood vessels by osmosis and include antibodies and blood-clotting protein's. Synonym: serum proteins. (05 Mar 2000) |
| silver proteins | <chemical> Compounds of silver and proteins used as topical anti-infective agents. Pharmacological action: anti-infective agents, local. (12 Dec 1998) |
| soy proteins | Proteins which are present in or isolated from soybeans. (12 Dec 1998) |
| neurofilament proteins | Type III intermediate filament proteins that assemble into neurofilaments, the major cytoskeletal element in nerve axons and dendrites. They consist of three distinct polypeptides, the neurofilament triplet. Types I, II, and IV intermediate filament proteins form other cytoskeletal elements such as keratins and lamins. It appears that the metabolism of neurofilaments is disturbed in alzheimer's disease, as indicated by the presence of neurofilament epitopes in the neurofibrillary tangles, as well as by the severe reduction of the expression of the gene for the light neurofilament subunit of the neurofilament triplet in brains of alzheimer's patients. (can j neurol sci 1990 aug;17(3):302) (12 Dec 1998) |
| structure proteins | Proteins whose role is for structure and support in tissue and within the cell; e.g., the collagens. (05 Mar 2000) |
| nuclear proteins | Proteins found in the nucleus of a cell. Do not confuse with nucleoproteins which are proteins conjugated with nucleic acids, that are not necessarily present in the nucleus. (12 Dec 1998) |