| macrolabia | Synonym: macrocheilia. Origin: macro-+ L. Labium, lip (05 Mar 2000) |
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| macroleukoblast | An unusually large leukoblast. (05 Mar 2000) |
| macrolide | <pharmacology> A group of antibiotics produced by various strains of Streptomyces that have a complex macrocyclic structure. They inhibit protein synthesis by blocking the 50S ribosomal subunit. Include erythromycin, carbomycin. Used clinically as broad spectrum antibiotics, particularly against gram-positive bacteria. (18 Nov 1997) |
| macrolide 2'-kinase | <enzyme> Inducible intracellular enzyme which inactivates 14-member ring macrolides at the 2'-oh of the d-desosamine moiety; from an erythromycin-resistant strain of E coli; GTP, itp and ATP can also act as donors; mph(2')i is encoded by mpha and mrx, which have been sequenced Registry number: EC 2.7.1.136 Synonym: oleandomycin 2'-phosphotransferase, macrolide 2'-phosphotransferase, macrolide 2'-phosphotransferase I, mph(2')i (26 Jun 1999) |
| macrolide glycosyltransferase | <enzyme> From streptomyces lividans; utilises udp-glucose as cofactor; substrates include macrolides with 12-, 14-, 15-, or 16-atom cyclic polyketide lactones; enzyme specific for the 2'-oh group of saccharide moieties attached to c-5 of the 16-atom lactone ring Registry number: EC 2.4.1.- Synonym: macrolide glucosyltransferase (26 Jun 1999) |
| macrolides | A group of organic compounds that contain a macrocyclic lactone ring linked glycosidically to one or more sugar moieties. (12 Dec 1998) |
| macrology | Long and tedious talk without much substance; superfluity of words. Origin: L. Macrologia, Gr.; long + discourse: cf. F. Macrologie. Source: Websters Dictionary (01 Mar 1998) |
| macromastia | Macromazia Abnormally large breasts. See: hypermastia. Origin: macro-+ G. Mastos, breast (05 Mar 2000) |
| macromelanosome | A large spherical melanosome (1 to 6 u in diameter) formed in the cytoplasm of melanocytes in cafe-au-lait spots and other melanocytic disorders. Synonym: macromelanosome. (05 Mar 2000) |
| macromelia | Abnormal size of one or more of the limbs. Synonym: megalomelia. Origin: macro-+ G. Melos, limb (05 Mar 2000) |
| macromere | A blastomere of large size, as in amphibians. Origin: macro-+ G. Meros, part (05 Mar 2000) |
| macromerozoite | A large merozoite. Synonym: megamerozoite. Origin: macro-+ G. Meros, part, + zoon, animal (05 Mar 2000) |
| macrominerals | Inorganic nutrients needed in relatively high daily amounts (i.e., more than 100 mg per day) e.g., calcium, phosphorus, sodium, etc. Synonym: macrominerals. (05 Mar 2000) |
| macromolecular chemistry | The chemistry of macromolecules (e.g., proteins, nucleic acids) and polymers (nylon, polyethylene, etc). (05 Mar 2000) |
| macromolecule | Biological term relating to large molecules including, proteins, nucleic acids and carbohydrates, but probably not phospholipids. (18 Nov 1997) |