| least-squares analysis | A principle of estimation in which the estimates of a set of parameters in a statistical model are those quantities minimizing the sum of squared differences between the observed values of a dependent variable and the values predicted by the model. (12 Dec 1998) |
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| linkage analysis | <genetics> Study aimed at establishing linkage between genes. Today linkage analysis serves as a way of gene-hunting and genetic testing. (12 Dec 1998) |