| histocompatibility antigens class I | Large transmembrane, polymorphic glycoproteins noncovalently associated with nonpolymorphic beta 2-microglobulin. In humans, three structural genes on chromosome 6 code for the HLA-a, HLA-b and HLA-c antigens. In mice, three genes named k, d, and l on chromosome 17 code for the h-2 antigens. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognised during graft rejection and restrict cell-mediated lysis of virus-infected cells. They are primarily associated with rheumatologic diseases and certain malignant disorders. (12 Dec 1998) |
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| histocompatibility antigens class II | Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural variation in the beta chains. The class II antigens in humans are called HLA-d antigens and are coded by a gene on chromosome 6. In mice, two genes named ia and i.e. On chromosome 17 code for the h-2 antigens. The antigens are found on B-lymphocytes, macrophages, epidermal cells, and sperm and are thought to mediate the competence of and cellular cooperation in the immune response. The term ia antigens used to refer only to the proteins encoded by the ia genes in the mouse, but is now used as a generic term for any class II histocompatibility antigen. (12 Dec 1998) |
| histocompatibility complex | A family of fifty or more genes on the sixth human chromosome that code for cell surface proteins and play a role in the immune response.Histocompatibility genes control the production of proteins on the outer membranes of tissue and blood cells, especially lymphocytes, and are vital elements in cell-cell recognition. The proteins also determine the level and type of immune response, and may serve other biochemical or immunologic functions. In the case of allografts, it is necessary to determine whether donor and recipient possess compatible sets of proteins (histocompatibility antigens), to minimise the likelihood of rejection. Histocompatibility testing (HLA tissue typing) provides this information. (05 Mar 2000) |
| histocompatibility gene | In laboratory animals, a gene which can elicit an immune response and thereby cause rejection of a homograft when tissue is transplanted from one individual to another; in humans, histocompatibility gene's control HLA antigens. Synonym: H gene. (05 Mar 2000) |
| histocompatibility testing | Identification of the major histocompatibility antigens of transplant donors and potential recipients, usually by serological tests. Donor and recipient pairs should be of identical abo blood group, and in addition should be matched as closely as possible for histocompatibility antigens in order to minimise the likelihood of allograft rejection. (12 Dec 1998) |
| histocompatible | The prefix histo- means tissue. The term histocompatible is literally tissue compatible. If a donor and recipient are histocompatible (like identical twins), a transplant will be easily accepted. (12 Dec 1998) |
| histocyte | <pathology> Long lived resident macrophage found within tissues. (11 Jan 1998) |
| histocytochemistry | Study of intracellular distribution of chemicals, reaction sites, enzymes, etc., by means of staining reactions, radioactive isotope uptake, selective metal distribution in electron microscopy, or other methods. (12 Dec 1998) |
| histocytological preparation techniques | Methods of preparing cells or tissues for examination and study of their origin, structure, function, or pathology. The methods include preservation, fixation, sectioning, staining, replica, or other technique to allow for viewing using a microscope. (12 Dec 1998) |
| histocytosis | A condition marked by the abnormal appearance of histiocytes (macrophages) in the blood. Lipid h., Niemann-Pick disease. Sinus h., a disorder of the lymph nodes in which the distended sinuses are completely or nearly completely, filled by histiocytes, as a result of active multiplication of the littoral cells. H. X, a generic term embracing eosinophilic granuloma, Letterer-Siwe disease and Hand-Schuller-Christian disease and indicating a shared common origin for the three entities. (16 Dec 1997) |
| histodifferentiation | The morphologic appearance of tissue characteristics during development. (05 Mar 2000) |
| histofluorescence | Fluorescence of the tissues under exposure to ultraviolet rays following the injection of a fluorescent substance or as a result of a natural fluorescing substance. (05 Mar 2000) |
| histogenesis | <embryology> The process of formation of a tissue, involving differentiation, morphogenesis and other processes such as angiogenesis, growth control, cellular infiltration etc. (18 Nov 1997) |
| histogenetic | <biology> Tissue-producing; connected with the formation and development of the organic tissues. See: Histogeny. Source: Websters Dictionary (01 Mar 1998) |
| histogenous | Formed by the tissues; e.g., the histogenous cells in an exudate arising from proliferation of the fixed tissue cells. Synonym: histiogenic. Origin: histo-+ G. -gen, producing (05 Mar 2000) |
Synonyms : Class II Antigen, Class II Histocompatibility Antigens, Class II Major Histocompatibility Antigens, I-A Antigen, I-A-Antigen, IA Antigen, Antigen, Class II, Antigen, I-A, Antigen, IA, Antigens, Class II, Antigens, Ia, Antigens, Ia-Like, Antigens, Immune-Associated
Synonyms : Crossmatchings, Tissue, HLA Typings, Histocompatibility Testings, Testing, Histocompatibility, Testings, Histocompatibility, Tissue Crossmatching, Tissue Crossmatchings, Tissue Typings, Typing, HLA, Typing, Tissue, Typings, HLA, Typings, Tissue
Synonyms :
Synonyms : Cytohistologic Preparation Technics, Cytohistologic Preparation Technique, Cytohistologic Preparation Techniques, Cytohistological Preparation Technic, Cytohistological Preparation Technics, Cytohistological Preparation Technique
Synonyms : Histologic Technic, Histologic Technics, Histologic Technique, Histologic Techniques, Histological Technics, Technic, Histologic, Technics, Histologic, Technique, Histologic, Techniques, Histologic, Histological Technic, Histological Technique
| histocompatibility |
The ability of a host to tolerate a tissue graft.
출처: www.genpromag.com/Glossary~LETTER~H.html
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| histocompatibility antigen |
A genetically determined antigen that determines the immune response to grafts.
출처: www.genpromag.com/Glossary~LETTER~H.html
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| histone |
One of a class of basic proteins that are complexed with DNA in chromosomes and that play a major role in determining the structure of eukaryotic nuclear chromosomes.
출처: www.modernhumanorigins.com/h.html
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| His |
Histidine (an amino acid).
출처: helios.bto.ed.ac.uk/bto/glossary/gh.htm
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| histone |
A type of basic protein that forms the unit around which DNA is coiled in the nucleosomes of eukaryotic chromosomes. Arginine and lysine rich basic proteins making up a substantial portion of eukaryotic nucleoprotein.
출처: helios.bto.ed.ac.uk/bto/glossary/gh.htm
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