| cholesterol monooxygenase (side-chain-cleaving) |
[EC 1.14.15.6] an enzyme of the oxidoreductase class that catalyzes the NADPH-dependent conversion of cholesterol to pregnenolone in a series of three reactions, successive hydroxylations of the 20 and 22 positions followed by cleavage of the side chain. The enzyme is a mitochondrial cytochrome P-450 acting as a terminal oxidase in an electron transport chain that also contains adrenodoxin and a flavoprotein. The reaction is the first step in the conversion of cholesterol to steroid hormones. Deficiency of the enzyme, an autosomal recessive trait, causes lipoid adrenal hyperplasia, a type of congenital adrenal hyperplasia (type I). Called also cholesterol desmolase and 20,22-desmolase.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| cholesterol p. |
pericarditis characterized by cholesterol-laden effusion, resulting from deposition of cholesterol crystals and subsequent inflammatory response including infiltration of the pericardium by lymphocytes, plasma cells, macrophages, and giant cells.
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| cholesterol p.’s |
small polypoid excrescences consisting of cholesterol and other lipids, seen projecting into the lumen of the gallbladder in cholesterolosis.
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| cholesterol sulfatase |
steryl-sulfatase.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| cholesterol t. |
see specifc tests, including Liebermann-Burchard t., Salkowski's t. (def. 2), Schultze's t. (def. 2).
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