| alcoh | alcohol, alcoholic, alcoholism |
|---|---|
| AlcR, alcR | alcohol rub |
| AOB | accessory olfactory bulb; alcohol on breath |
| APH | alcohol-positive history; alternative pathway hemolysis; aminoglycoside phosphotransferase; antepart... |
| AR | absolute risk; accounts receivable; achievement ratio; actinic reticuloid [syndrome]; active resista... |
| fatty alcohol | A long chain alcohol, analogous to the fatty acids, of which the fatty alcohol may be viewed as a reduction product; e.g., octadecanol from stearic acid. It is often found esterified in waxes. Synonym: wax alcohol. (05 Mar 2000) |
|---|---|
| foetal alcohol effects | A softer diagnosis than foetal alcohol syndrome (FAS). The diagnosis of possible FAE is considered when: 1. The person has some signs of FAS; 2. The person does not meet all of the necessary criteria for FAS; and 3. There is a history of alcohol exposure before birth. (12 Dec 1998) |
| foetal alcohol syndrome | <syndrome> The most common cause of defective cerebral development in industrialised nations, affecting 1 in 700 live births in the United States. This clinical syndrome results from the direct toxic effects of alcohol on the developing foetus. Growth retardation, mental retardation, small brain and heart valve lesions are common. Infants can be identified by close set eyes, small head, small nasal bridge, reduction in the vermilion border of the upper lip, eye folds and small teeth. (27 Sep 1997) |
| 4-sulfobenzyl alcohol dehydrogenase | <enzyme> Catalyses the formation of 4-sulfobenzaldehyde from 4-sulfobenzyl alcohol; amino acid sequence given in first source Registry number: EC 1.1.1.- Synonym: p-sulfobenzyl alcohol dehydrogenase, tsac protein, tsac gene product (26 Jun 1999) |
| long-chain-alcohol dehydrogenase | <enzyme> Catalyses reversibly the oxidation of a long-chain alcohol in the presence of nad to a long-chain acid anion and NADH Registry number: EC 1.1.1.192 Synonym: fatty alcohol-nad+ oxidoreductase (26 Jun 1999) |
| long-chain-alcohol O-fatty-acyltransferase | <enzyme> Catalyses the final step in biosynthesizing storage liquid waxes from long chain fatty acyl CoA and fatty alcohols; forming predominantly c42 wax esters Registry number: EC 2.3.1.75 Synonym: acyl-coenzyme a-alcohol transacylase, aca transacylase, acyl-CoA-alcohol transacylase, wax-ester synthase (26 Jun 1999) |
| abnormalities, drug-induced | Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment. (12 Dec 1998) |
| activity, drug | A measure of the physiological response a drug produces in the body. A less active drug produces less response (and visa versa). (12 Dec 1998) |
| addictive drug | Any drug that creates a certain degree of euphoria and has a strong potential for addiction. (05 Mar 2000) |
| adverse drug reaction reporting systems | Systems developed for collecting reports from government agencies, manufacturers, hospitals, physicians, and other sources on adverse drug reactions. (12 Dec 1998) |
| akathisia, drug-induced | Motor restlessness with sensations of quivering and an urge to move about constantly resulting from the use of certain drugs, such as neuroleptic drugs, which affect the extrapyramidal region of the brain. This differs from dyskinesia, drug-induced in that long-term antipsychotic drug exposure is significantly correlated with the increased prevalence of akathisia while there is no such correlation with dyskinesia. The primary observable distinction between tardive akathisia and dyskinesia appears to be in the repetitive, stereotypy of the dyskinesic movements (lip smacking, for example), while akathisia is associated with anxiety, restlessness, and agitation (psychomotor agitation). (12 Dec 1998) |
| antineoplastic drug | A drug that stops or slows the maturation and spread of tumour cells (benign or malignant). (09 Oct 1997) |
| maintenance drug therapy | In chemotherapy, systematic dosage at a level that maintains protection against exacerbation. (05 Mar 2000) |
| rational drug design | <pharmacology> Modeling the molecular structure of the target of a drug, for example, an antigen, and then designing a drug that will attack it. (17 Dec 1997) |
| receptors, drug | Proteins that bind specific drugs with high affinity and trigger intracellular changes influencing the behaviour of cells. Drug receptors are generally thought to be receptors for some endogenous substance not otherwise specified. (12 Dec 1998) |