| 3-methylcholanthrene |
a highly carcinogenic polycyclic aromatic hydrocarbon synthesized by pyrolytic degradation of cholic acid, deoxycholic acid, or cholesterol. It is a procarcinogen that requires metabolic activation to exert a mutagenic effect and is widely used in laboratory studies of chemical carcinogenesis. Abbreviated MCA.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| 3-methylcrotonic acid |
crotonic acid methylated at the 3 carbon; it is excreted at elevated levels in urine when 3-methylcrotonoyl-CoA carboxylase activity is impaired.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| 3-methylcrotonyl |
the radical of 3-methylcrotonic acid; the thioester formed with coenzyme A, 3-methylcrotonyl CoA, is an intermediate in the degradation of leucine.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| 3-methylcrotonyl CoA carboxylase deficiency |
an autosomal recessive aminoacidopathy due to deficiency of methylcrotonoyl-CoA carboxylase, characterized by increased urine levels of 3-methylcrotonylglycine, 3-methylcrotonic acid, and 3-hydroxyisovaleric acid and variable presentation of mental retardation, central nervous system dysfunction, and muscular atrophy. Written also β-methylcrotonyl CoA carboxylase deficiency.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| 3-methylcrotonylglycine |
a conjugate of 3-methylcrotonic acid and glycine, formed and excreted in excess in the urine when 3-methylcrotonoyl-CoA carboxylase activity is impaired.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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