| MHR | major histocompatibility region; malignant hyperthermia resistance; maternal heart rate; maximal hea... |
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| MHS | major histocompatibility system; malignant hyperthermia in swine; malignant hyperthermia syndrome; m... |
| MIP | macrophage inflammatory protein; major intrinsic protein; maximum inspiratory pressure; maximum inte... |
| MM | macromolecule; Maelzels metronome; major medical [insurance]; malignant melanoma; manubrium to malle... |
| MOP | major organ profile; medical outpatient |
| hippocampus major | <anatomy> Area of mammallian brain and an important preparation for the study of synaptic plasticity. The hippocampus has been known since the 1950s to be important for long term memory storage in humans and other mammals, it is essential for initial storing of long-term memory for a period of days to weeks before the memory trace is consolidated elsewhere. Also the site of long-term synaptic plasticity: see long-term potentiation, which is exhibited by defined synaptic pathways in the hippocampus. (18 Nov 1997) |
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| psoas major | <anatomy, muscle> Origin, bodies of vertebrae and intervertebral disks from the twelfth thoracic to the fifth lumbar, and transverse processes of the lumbar vertebrae; insertion, forms a common insertion with iliacus muscle into lesser trochanter of femur; action, flexes hip joint; nerve supply, lumbar plexus (ventral rami of first, second and usually third lumbar spinal nerves). Synonym: musculus psoas major, greater psoas muscle. (05 Mar 2000) |
| spina tympanica major | The anterior edge of the tympanic notch (of Rivinus). Synonym: spina tympanica major. (05 Mar 2000) |
| nervus occipitalis major | <anatomy, nerve> Medial branch of the dorsal primary ramus of the second cervical nerve; sends branches to the semispinalis capitis and multifidus cervicis, but is mainly cutaneous, supplying the back part of the scalp. Synonym: nervus occipitalis major. (05 Mar 2000) |
| nervus palatinus major | <anatomy, nerve> A branch of the pterygopalatine ganglion that passes downward through the greater palatine canal to supply the mucosa and glands of the hard palate, and the anterior part of the soft palate. Synonym: nervus palatinus major. (05 Mar 2000) |
| nervus petrosus major | <anatomy, nerve> The parasympathetic root of the pterygopalatine ganglion; a branch from the genu of the facial nerve exiting via the hiatus of the facial canal and running in a groove on the anterior surface of the petrous part of the temporal bone beside the foramen lacerum to join the deep petrosal nerve, thus forming the nerve of the pterygoid canal, which passes through the pterygoid canal to reach the pterygopalatine ganglion. Synonym: nervus petrosus major, greater petrosal nerve. (05 Mar 2000) |
| nervus splanchnicus major | <anatomy, nerve> Uppermost of the abdominopelvic splanchnic which arises from the fifth or sixth to the ninth or tenth thoracic sympathetic ganglia in the thorax and passes downward along the bodies of the thoracic vertebrae, penetrating the diaphragm to join the coeliac plexus; conveys presynaptic sympathetic fibres to the coeliac ganglia, and visceral afferent fibres from the coeliac plexus. Synonym: nervus splanchnicus major. (05 Mar 2000) |
| sulcus palatinus major | A groove on both the body of the maxilla and the perpendicular plate of the palatine bone; when the bones are articulated the grooves form the greater palatine canal. Synonym: sulcus palatinus major, pterygopalatine groove, sulcus for greater palatine nerve, sulcus pterygopalatinus. (05 Mar 2000) |
| depression, major | Major depression is manifested by a combination of symptoms (see Depression, symptoms of) that interfere with the ability to work, sleep, eat, and enjoy once pleasurable activities. These disabling episodes of depression can occur once, twice, or several times in a lifetime. (12 Dec 1998) |
| ductus sublingualis major | The duct that drains the anterior portion of the sublingual gland; it opens at the sublingual papilla. Synonym: ductus sublingualis major, Bartholin's duct. (05 Mar 2000) |
| incisura ischiadica major | The deep indentation in the posterior border of the hip bone at the point of union of the ilium and ischium. Synonym: incisura ischiadica major, iliosciatic notch, sacrosciatic notch. (05 Mar 2000) |
| insurance, major medical | Insurance providing a broad range of medical services and supplies, when prescribed by a physician, whether or not the patient is hospitalised. It frequently is an extension of a basic policy and benefits will not begin until the basic policy is exhausted. (12 Dec 1998) |
| teres major | <anatomy, muscle> Origin, inferior angle and lower third of border of scapula; insertion, medial border of intertubercular groove of humerus; action, adducts and extends arm and rotates it medially; nerve supply, lower subscapular from posterior cord of brachial plexus (fifth and sixth cervical spinal nerves). Synonym: musculus teres major. (05 Mar 2000) |
| thalassaemia major | The dire disease also known as beta thalassaemia. The clinical picture of this form of anaemia was first described in 1925 by the paediatrician thomas benton cooley. Other names for the disease are cooley's anaemia and mediterranean anaemia. The term thalassaemia was coined by the nobel prise winning pathologist george whipple and the professor of paediatrics william bradford at u. Of rochester because thalassa in greek means the sea (like the mediterrranean sea) + -aemia means in the blood so thalassaemia means sea in the blood. Thalassaemia is not just one disease. It is a complex contingent of genetic (inherited) disorders all of which involve underproduction of haemoglobin, the indispensable molecule in red blood cells that carries oxygen. The globin part of normal adult haemoglobin is made up of 2 alpha and 2 beta polypeptide chains. In beta thalassaemia, there is a mutation (change) in both beta globin chains leading to underproduction (or absence) of beta chains, underproduction of haemoglobin, and profound anaemia. The gene for beta thalassaemia is relatively frequent in people of mediterranean origin (for example, from italy and greece). Children with this disease inherit one gene for it from each parent (and so are said to be homozygous for beta thalassaemia). The parents are carriers (heterozygotes) with just one thalassaemia gene, are said to have thalassaemia minor, and are essentially normal. Their children affected with beta thalassaemia seem entirely normal at birth (because at birth we still have predominantly foetal haemoglobin which does not contain beta chains) but the anaemia emerges in the first few months of life and becomes progressively more severe leading to pallor and easy fatiguability, failure to thrive (grow), bouts of fever (due to infections) and diarrhoea. Treatment based on blood transfusions is helpful but not curative. Gene therapy will, it is hoped, be applicable to this disease. (12 Dec 1998) |
| trochanter major | A strong process at the proximal and lateral part of the shaft of the femur, overhanging the root of the neck; it gives attachment to the gluteus medius and minimus, piriformis, obturator internus and externus, and gemelli muscles. Synonym: trochanter major. (05 Mar 2000) |