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ellis-van creveld syndrome <radiology> Chondro-ectodermal dysplasia, hereditary (especially seen in Amish of Pennsylvania), polydactyly (100%), congenital heart disease (60%), abnormalities of cutaneous appendages (skin, hair, nails) More info: Ellis-van Creveld syndrome
(12 Dec 1998)
exon trapping vincent van buren <molecular biology, technique> A technique used to identify vector. The vector has two exons that are normal, splicedtogether in a transcript.Fragments of DNA can be inserted into the intron, and when the insert is an exon, the exon is splicedinto the transcript, thereby giving a longer transcript that can be detected by Northern blotanalysis.
(09 Oct 1997)
Le Bel-van't Hoff rule The number of stereoisomers of an organic compound is 2n where n represents the number of asymmetric carbon atoms (unless there is an internal plane of symmetry). A corollary of their simultaneously announced conclusions, in 1874, that the most probable orientation of the bonds of a carbon atom linked to four groups or atoms is toward the apexes of a tetrahedron, and that this accounted for all then-known phenomena of molecular asymmetry (which involved a carbon atom bearing four different atoms or groups).
See: stereoisomerism.
(05 Mar 2000)
Lobry de Bruyn-van Ekenstein transformation The conversion of glucose to fructose and mannose in dilute alkali by enolization adjacent to the carbonyl group to form an enediol, a reaction analogous to certain biochemical transformations.
(05 Mar 2000)
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