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sporulation-specific cell wall hydrolase <enzyme> From bacillus subtilis; 255-amino acid protein mw 27.146 kD; hydrolyzes both vegetative cell walls and spore peptidoglycan genbank d14666
Registry number: EC 3.-
Synonym: cwlc gene product
(26 Jun 1999)
non-specific 1. Not due to any single known cause, as to a particular pathogen.
2. Not directed against a particular agent, but rather having a general effect, as non-specific therapy.
(18 Nov 1997)
non-specific anergy A reduction of the normal or usual immunologic responses because of unrelated intervening disease.
Synonym: non-specific anergy.
(05 Mar 2000)
non-specific cholinesterase <enzyme> An enzyme that breaks down acetylcholine tostop its action.
(22 May 1997)
non-specific protein A protein substance that elicits a response not mediated by specific antigen-antibody reaction.
(05 Mar 2000)
non-specific system <physiology> A physiological term denoting that part of the brainstem reticular formation that plays a central role in the organism's bodily and behavorial alertness.
It extends as a diffusely organised neural apparatus through the central region of the brainstem into the subthalamus and the intralaminar nuclei of the thalamus; by its ascending connections it affects the function of the cerebral cortex in the sense of behavioural responsiveness; its descending (reticulospinal) connections transmit its activating influence upon bodily posture and reflex mechanisms (e.g., muscle tonus), in part by way of the gamma motor neurons.
See: reticular formation.
Synonym: non-specific system.
(05 Mar 2000)
non-specific therapy The injection of a foreign protein, typhoid vaccine, etc., to induce fever in the treatment of certain diseases, especially those of a parasyphilitic nature.
Synonym: phlogotherapy.
(05 Mar 2000)
non-specific urethritis Urethritis not resulting from gonococcal, chlamydial, or other specific infectious agents.
Synonym: simple urethritis.
(05 Mar 2000)
non-specific vaginitis bacterial vaginosis
sugar-non-specific nuclease <enzyme> An exocytoplasmic sugar-non-specific nuclease that is able to degrade linear or covalently closed circular double-stranded DNA as well as single-stranded DNA or RNA; from cyanobacterium anabaena; mw 29 kD; amino acid sequence has been determined
Registry number: EC 3.1.-
Synonym: nuca gene product, anabaena
(26 Jun 1999)
IgA-specific serine endopeptidase <enzyme> Extracellular microbial enzymes whose only substrate is human IgA of the iga1 subclass; cleave the immunoglobulin at a specific internal prolyl-threonyl peptide bond in the heavy chain to yield intact faba and fca fragments; consider also EC 3.4.24.13
Registry number: EC 3.4.21.72
Synonym: immunoglobulin a(1) protease, iga1 protease, immunoglobulin a1 protease, IgA protease
(26 Jun 1999)
organ-specific Denoting or pertaining to a serum produced by the injection of the cells of a certain organ or tissue that, when injected into another animal, destroys the cells of the corresponding organ.
(05 Mar 2000)
organ-specific antigen A heterogenetic antigen with organ specificity; e.g., in addition to species-specific antigen, kidney of one species contains antigen that is identical to that in kidney of other species.
Synonym: tissue-specific antigen.
(05 Mar 2000)
tail-specific protease <enzyme> Selectively degrades proteins with nonpolar c termini
Registry number: EC 3.4.99.-
Synonym: tsp protease, prc protein, prc gene product
(26 Jun 1999)
tissue-specific antigen A heterogenetic antigen with organ specificity; e.g., in addition to species-specific antigen, kidney of one species contains antigen that is identical to that in kidney of other species.
Synonym: tissue-specific antigen.
(05 Mar 2000)
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