| tryptophan hydroxylase | <enzyme> An enzyme that catalyses the hydroxylation of tryptophan to 5-hydroxytryptophan in the presence of NADPH and molecular oxygen. It is important in the biosynthesis of serotonin. Chemical name: L-tryptophan,tetrahydropteridine:oxygen oxidoreductase (5-hydroxylating) Registry number: EC 1.14.16.4 (12 Dec 1998) |
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| tryptophan oxygenase | <enzyme> A protohemoprotein. Forms formylkynurenine from l-tryptophan and molecular oxygen. Chemical name: L-Tryptophan:oxygen 2,3-oxidoreductase (decyclizing) Registry number: EC 1.13.11.11 (12 Dec 1998) |
| tryptophan pyrrolase | An oxidoreductase catalyzing the reaction of l-tryptophan and O2 to produce l-N-formylkynurenine; an adaptive enzyme, the level (in the liver) being controlled by adrenal hormones; a step in tryptophan catabolism; also, a step in the synthesis of NAD+ from tryptophan. Synonym: pyrrolase, tryptophan oxygenase, tryptophan pyrrolase, tryptophanase. (05 Mar 2000) |
| tryptophan synthase | <enzyme> An enzyme that catalyses the conversion of l-serine and 1-(indol-3-yl)glycerol 3-phosphate to l-tryptophan and glyceraldehyde 3-phosphate. It is a pyridoxal phosphate protein that also catalyses the conversion of serine and indole into tryptophan and water and of indoleglycerol phosphate into indole and glyceraldehyde phosphate. Chemical name: L-Serine hydro-lyase (adding indoleglycerol-phosphate) Registry number: EC 4.2.1.20 (12 Dec 1998) |
| tryptophan synthetase | <enzyme> An enzyme that catalyses the conversion of l-serine and 1-(indol-3-yl)glycerol 3-phosphate to l-tryptophan and glyceraldehyde 3-phosphate. It is a pyridoxal phosphate protein that also catalyses the conversion of serine and indole into tryptophan and water and of indoleglycerol phosphate into indole and glyceraldehyde phosphate. Chemical name: L-Serine hydro-lyase (adding indoleglycerol-phosphate) Registry number: EC 4.2.1.20 (12 Dec 1998) |
| tryptophan-trna ligase | <enzyme> An enzyme that activates tryptophan with its specific transfer RNA. Chemical name: L-Tryptophan:tRNA(Trp) ligase (AMP-forming) Registry number: EC 6.1.1.2 (12 Dec 1998) |
| tryptophanase | <enzyme> An enzyme that catalyses the conversion of l-tryptophan and water to indole, pyruvate, and ammonia. It is a pyridoxal-phosphate protein, requiring k+. It also catalyses 2,3-elimination and beta-replacement reactions of some indole-substituted tryptophan analogs of l-cysteine, l-serine, and other 3-substituted amino acids. Chemical name: L-Tryptophan indole-lyase (deaminating) Registry number: EC 4.1.99.1 (12 Dec 1998) |
| tryptophanuria | Enhanced urinary excretion of tryptophan. Tryptophanuria with dwarfism, a syndrome of dwarfism, mental defect, cutaneous photosensitivity, and gait disturbance associated with tryptophanuria; autosomal recessive inheritance. (05 Mar 2000) |
| tryst | 1. Trust. 2. An appointment to meet; also, an appointed place or time of meeting; as, to keep tryst; to break tryst. To bide tryst, to wait, at the appointed time, for one with whom a tryst or engagement is made; to keep an engagement or appointment. "The tenderest-hearted maid That ever bided tryst at village stile." (Tennyson) Origin: OE. Trist, tryst, a variant of trust; cf. Icel. Treysta to make trusty, fr. Traust confidence, security. See Trust. Source: Websters Dictionary (01 Mar 1998) |