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  • thromboxane
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  • thromboxane
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  • thromboxane a.s.2.t
    Æ®·Òº¹¼¼ÀÎ A.S.2.T
  • thromboxane synthetase
    Æ®·Òº¹¼¼ÀÎÇÕ¼ºÈ¿¼Ò
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thrombotic thrombocytopenic purpura A rapidly fatal or occasionally protracted disease with varied symptoms in addition to purpura, including signs of central nervous system involvement, due to formation of fibrin or platelet thrombi in arterioles and capillaries in many organs.
Synonym: Moschcowitz' disease.
(05 Mar 2000)
thrombotonin 5-hydroxytryptamine
thromboxane <biochemistry> Arachidonic acid metabolites produced by the action of thromboxane synthetase on prostaglandin cyclic endoperoxides. Thromboxane A2 (TxA2) is a potent inducer of platelet aggregation and release and although unstable, the activation of platelets leads to the further production of TxA2. Also causes arteriolar constriction. Another endoperoxide product, prostacyclin, has the opposite effects.
(18 Nov 1997)
thromboxane a2 <chemical> An unstable intermediate between the prostaglandin endoperoxides and thromboxane b2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (rcs).
Chemical name: Thromboxa-5,13-dien-1-oic acid, 9,11-epoxy-15-hydroxy-, (5Z,9alpha,11alpha,13E,15S)-
(12 Dec 1998)
thromboxane b2 <chemical> A stable, physiologically active compound formed in vivo from the prostaglandin endoperoxides. It is important in the platelet-release reaction (release of ADP and serotonin).
Chemical name: Thromboxa-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9alpha,13E,15S)-
(12 Dec 1998)
thromboxane dehydrogenase <enzyme> Converts thromboxane b2 to 11-dehydro-thromboxane b2, but not the reverse reaction; uses nad but not nadp as cofactor; only attacks the 11-hydroxy group of txb2
Registry number: EC 1.1.1.-
Synonym: thromboxane b2 dehydrogenase, 11-hydroxythromboxane b2 dehydrogenase, 11-hydroxy-txb2 dehydrogenase
(26 Jun 1999)
thromboxane-a synthase <enzyme> An enzyme found predominantly in platelet microsomes. It catalyses the conversion of pgg(2) and pgh(2) (prostaglandin endoperoxides) to thromboxane a2.
Chemical name: (5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate thromboxane-A(2)-isomerase
Registry number: EC 5.3.99.5
(12 Dec 1998)
thromboxanes Physiologically active compounds found in many organs of the body. They are formed in vivo from the prostaglandin endoperoxides and cause platelet aggregation, contraction of arteries, and other biological effects. Thromboxanes are important mediators of the actions of polyunsaturated fatty acids transformed by cyclooxygenase.
(12 Dec 1998)
thrombozyme <haematology> Traditional name for substance in plasma that converts prothrombin to thrombin. Now known not to be a single substance. (See thrombin).
(18 Nov 1997)
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thrombolytic used to break up a thrombus (stationary blood clot)
Ãâó: www.chfpatients.com/glossary_2.htm
thromboembolism blockage of an artery caused by a blood clot moving into an artery too small to carry it. Can cause heart attack or stroke
Ãâó: www.chfpatients.com/glossary_2.htm
thrombosis The development of a clot in a vein or an artery.
Ãâó: cll.ucsd.edu/glossaryt.htm
thrombocyte A synonym for platelet.
Ãâó: cll.ucsd.edu/glossaryt.htm
thrombocyte a blood cell that helps to control bleeding by inducing clotting. Also called a platelet.
Ãâó: www.lymphomainfo.net/lymphoma/glossary.html
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