| thrombospondins | A family of related, adhesive glycoproteins which are synthesised, secreted, and incorporated into the extracellular matrix of a variety of cells, including alpha granules of platelets following thrombin activation and endothelial cells. They interact with a number of blood coagulation factors and anticoagulant factors. Five distinct forms have been identified, thrombospondin 1, -2, -3, -4, and cartilage oligomeric matrix protein (comp). They are involved in cell adhesion, platelet aggregation, cell proliferation, angiogenesis, tumour metastasis, vascular smooth muscle growth, and tissue repair. (12 Dec 1998) |
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| thrombostasis | Local arrest of the circulation by thrombosis. Origin: thrombo-+ G. Stasis, a standing (05 Mar 2000) |
| thrombosthenin | <cell biology> Obsolete name for platelet contractile protein: now known to be actomyosin (which makes up 15-20% of the total platelet protein). (18 Nov 1997) |
| thrombotic | Relating to, caused by, or characterised by thrombosis. (05 Mar 2000) |
| thrombotic disease due to protein c deficiency | Protein C is a protein in plasma that enters into the cascade of biochemical events leading to the formation of a clot. Deficiency of protein c results in thrombotic (clotting) disease and excess platelets with recurrent thrombophlebitis (inflammation of the vein that occurs when a clot forms). The clot can break loose and travel through the blood stream (thromboembolism) to the lungs causing a pulmonary embolism, brain causing a stroke (cerebrovascular accident), heart causing an early heart attack, skin causing what in the newborn is called neonatal purpura fulminans, the adrenal gland causing haemorrhage with abdominal pain, abnormally low blood pressure (hypotension), and salt loss. Protein c deficiency is due to possession of one gene (heterozygosity) in chromosome band 2q13-14. The possession of two such genes (homozygosity) is usually lethal. (12 Dec 1998) |
| thrombotic gangrene | Gangrene due to occlusion of an artery by a thrombus. (05 Mar 2000) |
| thrombotic hydrocephalus | Increase in cerebrospinal fluid and of intracranial pressure following thrombosis of the cerebral veins or sinuses; caused by septic infection, dehydration, tuberculosis, typhoid, leukaemia, and other conditions. (05 Mar 2000) |
| thrombotic infarct | An infarct caused by a thrombus. (05 Mar 2000) |
| thrombotic microangiopathy | Thrombosis within small blood vessels, as in thrombotic thrombocytopenic purpura. (05 Mar 2000) |
| thrombotic phlegmasia | An extreme edematous swelling of the leg following childbirth, due to thrombosis of the iliofemoral veins. Synonym: leukophlegmasia dolens, milk leg, puerperal phlebitis, thrombotic phlegmasia, white leg. (05 Mar 2000) |
| thrombotic thrombocytopenic purpura | A rapidly fatal or occasionally protracted disease with varied symptoms in addition to purpura, including signs of central nervous system involvement, due to formation of fibrin or platelet thrombi in arterioles and capillaries in many organs. Synonym: Moschcowitz' disease. (05 Mar 2000) |
| thrombotonin | 5-hydroxytryptamine |
| thromboxane | <biochemistry> Arachidonic acid metabolites produced by the action of thromboxane synthetase on prostaglandin cyclic endoperoxides. Thromboxane A2 (TxA2) is a potent inducer of platelet aggregation and release and although unstable, the activation of platelets leads to the further production of TxA2. Also causes arteriolar constriction. Another endoperoxide product, prostacyclin, has the opposite effects. (18 Nov 1997) |
| thromboxane a2 | <chemical> An unstable intermediate between the prostaglandin endoperoxides and thromboxane b2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (rcs). Chemical name: Thromboxa-5,13-dien-1-oic acid, 9,11-epoxy-15-hydroxy-, (5Z,9alpha,11alpha,13E,15S)- (12 Dec 1998) |
| thromboxane b2 | <chemical> A stable, physiologically active compound formed in vivo from the prostaglandin endoperoxides. It is important in the platelet-release reaction (release of ADP and serotonin). Chemical name: Thromboxa-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9alpha,13E,15S)- (12 Dec 1998) |
| thromboembolism |
(noun) the blocking of a blood vessel by a thrombus (blood clot) that has become detached from its site of formation
출처: www.orgsites.com/fl/adjuvantdisease/_pgg9.php3
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| thrombocyte |
Also called a platelet. Component of blood that aids in clotting.
출처: www.clevelandclinic.org/heartcenter/pub/glossary/t...
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| thromboplastin |
THROM-bo-PLAS-tin A protein released from blood vessel walls following injury that converts prothrombin to thrombin. 717
출처: www.mhhe.com/biosci/genbio/life/glossaryt.mhtml
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| thrombus |
THROM-bus A blood clot that blocks a blood vessel. 717
출처: www.mhhe.com/biosci/genbio/life/glossaryt.mhtml
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| thrombus |
clot formed in blood during life
출처: www.southalabama.edu/alliedhealth/cls/Ravine/gloss...
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