| tetrahydric | Denoting a compound containing four ionizable hydrogen atoms (four acid groups). (05 Mar 2000) |
|---|---|
| tetrahydro- | <prefix> Prefix denoting attachment of four hydrogen atoms; e.g., tetrahydrofolate, H4folate. (05 Mar 2000) |
| tetrahydrocannabinol | <chemical> The delta(1)-3,4-trans-isomer (also referred to as the delta(9)-isomer) is the major pharmacologically active constituent of cannabis sativa l. (marihuana, hashish). Dronabinol, a synthetic form of tetrahydrocannabinol, is used to treat the wasting condition associated with aids and also cancer patients undergoing chemotherapy. Pharmacological action: antiemetics, appetite stimulants, hallucinogens. Chemical name: 6H-Dibenzo(b,d)pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR-trans)- (12 Dec 1998) |
| tetrahydrocannibanol | <chemical> This is the primary intoxicant in marijuana, Cannabis sativa. It is marketed as Marinol and can be legally prescribed to treat nausea associated with chemotherapy and radiation treatment. It has also proven useful in treating glaucoma. (09 Oct 1997) |
| tetrahydrocortisol | <chemical> Chemical name: Pregnan-20-one, 3,11,17,21-tetrahydroxy-, (3alpha,5beta,11beta)- (12 Dec 1998) |
| tetrahydrocortisone | <chemical> Chemical name: Pregnane-11,20-dione, 3,17,21-trihydroxy-, (3alpha,5beta)- (12 Dec 1998) |
| tetrahydrofolate dehydrogenase | <enzyme> An enzyme of the oxidoreductase class that catalyses the reaction 7,8-dihyrofolate and NADPH to yield 5,6,7,8-tetrahydrofolate and NADPH+, producing reduced folate for amino acid metabolism, purine ring synthesis, and the formation of deoxythymidine monophosphate. Methotrexate and other folic acid antagonists used as chemotherapeutic drugs act by inhibiting this enzyme. Chemical name: 5,6,7,8-Tetrahydrofolate:NADP+ oxidoreductase Registry number: EC 1.5.1.3 (12 Dec 1998) |
| tetrahydrofolate methyltransferase | Tetrahydropteroylglutamate methyltransferase; methionine-homocysteine methyltransferase;an enzyme that catalyses the reaction of N5-methyltetrahydrofolate with l-homocysteine to form tetrahydrofolate and l-methionine; a cobalamin-requiring enzyme; a deficiency of this enzyme results in an accumulation of l-homocysteine and neurological abnormalities. Synonym: tetrahydrofolate methyltransferase. (05 Mar 2000) |
| tetrahydrofolic acid | The active coenzyme form of folic acid; participates in one-carbon metabolism. Synonym: coenzyme F. (05 Mar 2000) |
| tetrahydromethanopterin S-methyltransferase | <enzyme> Catalyses transfer of methyl groups from methyltetrahydromethanopterin to 2-mercaptoethanesulfonate; component of methane synthesizing complex of methanobacterium thermoautotrophicum; enzyme contains 5-hydroxybenzimidazolyl cobamide Registry number: EC 2.1.1.86 Synonym: thmpt methyltransferase, tetrahydromethanopterin methyltransferase, meh4mpt-com methyltransferase, methyltetrahydromethanopterin-coenzyme m methyltransferase, 5-methyl-5,6,7,8-tetrahydromethanopterin - 2-mercaptoethanesulfonate 2-methyltransferase, n5-methyltetrahydromethanopterin-coenzyme m methyltransferase, n(5)-methyltetrahydromethanopterin-coenzyme m methyltransferase (26 Jun 1999) |
| tetrahydronaphthalenes | Partially saturated 1,2,3,4-tetrahydronaphthalene compounds. (12 Dec 1998) |
| tetrahydropapaveroline | <chemical> 1-(3,4-dihydroxybenzyl)-1,2,3,4-tetrahydro-6,7-isoquinolinediol. A leukomaine (animal alkaloid) formed in brain and liver from dopamine and l-dopa; it may be implicated in psychiatric problems. Chemical name: 6,7-Isoquinolinediol, 1-((3,4-dihydroxyphenyl)methyl)-1,2,3,4-tetrahydro- (12 Dec 1998) |
| tetrahydroprotoberberine oxidase | <enzyme> From berberis wilsoniae; catalyses in the presence of oxygen the removal of four hydrogen atoms from the c ring of tetrahydroprotoberberines with production of 4 mol of h2o2 and h2o Registry number: EC 1.3.3.- Synonym: thpb oxidase, tetrahydroberberine oxidase (26 Jun 1999) |
| tetrahydrouridine | <chemical> 1-(beta-d-ribofuranosyl)-4-hydroxy-3,4,5-tetrahydro-pyrimidin-2(1h)-one. An inhibitor of nucleotide metabolism. Pharmacological action: antimetabolites. Chemical name: 2(1H)-Pyrimidinone, tetrahydro-4-hydroxy-1-beta-D-ribofuranosyl- (12 Dec 1998) |
| tetrahydroxynaphthalene reductase | <enzyme> Catalyses the NADPH-dependent reduction of 1,3,6,8-tetrahydroxynaphthalene into scytalone and 1,3,8-trihydroxynaphthalene into vermelone; genbank l22309 Registry number: EC 1.3.1.50 Synonym: t4hn reductase, scytalone-nadp(+) delta(5)-oxidoreductase, NADPH-dependent tetrahydroxynaphthalene reductase, polyhydroxynaphthalene reductase, thr1 gene product, 1,3,8-trihydroxynaphthalene reductase (26 Jun 1999) |