| genes, src | Retrovirus-associated DNA sequences (src) originally isolated from the rous sarcoma virus (rsv). The proto-oncogene src (c-src) codes for a protein that is a member of the tyrosine kinase family and was the first proto-oncogene identified in the human genome. The human c-src gene is located at 20q12-13 on the long arm of chromosome 20. (12 Dec 1998) |
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| genes, structural | Genes that code for proteins required for the enzymatic and structural functions of cells. They include developmental and differentiated genes. (12 Dec 1998) |
| genes, structural, bacterial | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of bacterial cells. (12 Dec 1998) |
| genes, structural, fungal | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of fungal cells. (12 Dec 1998) |
| genes, structural, helminth | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of helminthic cells. (12 Dec 1998) |
| genes, structural, insect | DNA sequences that code for RNA and for proteins required for the enzymatic and structural function of insect cells. (12 Dec 1998) |
| genes, structural, neoplasm | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of neoplastic cells. (12 Dec 1998) |
| genes, structural, plant | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of plant cells. (12 Dec 1998) |
| genes, structural, protozoan | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of protozoan cells. (12 Dec 1998) |
| genes, structural, viral | DNA or RNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of viral cells. (12 Dec 1998) |
| genes, suppressor | Genes that inhibit expression of a previous mutation. They allow the wild-type phenotype to be wholly or partially restored. (12 Dec 1998) |
| genes, suppressor, tumour | Genes that inhibit expression of the tumourigenic phenotype. They are normally involved in holding cellular growth in check. When tumour suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and deregulated growth is possible. (12 Dec 1998) |
| genes, switch | Genes that cause the epigenotype (i.e., the interrelated developmental pathways through which the adult organism is realised) to switch to an alternate cell lineage-related pathway. Switch complexes control the expression of normal functional development as well as oncogenic transformation. (12 Dec 1998) |
| genes, synthetic | Biologically functional sequences of DNA chemically synthesised in vitro. (12 Dec 1998) |
| genes, tat | DNA sequences that form the coding region for the protein responsible for trans-activation of transcription (tat) in human immunodeficiency virus (HIV). (12 Dec 1998) |